2007
The Role of the Human Orbitofrontal Cortex in Taste and Flavor Processing
SMALL DM, BENDER G, VELDHUIZEN MG, RUDENGA K, NACHTIGAL D, FELSTED J. The Role of the Human Orbitofrontal Cortex in Taste and Flavor Processing. Annals Of The New York Academy Of Sciences 2007, 1121: 136-151. PMID: 17846155, DOI: 10.1196/annals.1401.002.Peer-Reviewed Original ResearchConceptsHuman orbitofrontal cortexOrbitofrontal cortexSensory inputDistinct sensory inputsMultiple sensory inputsHigher-order gustatory corticesNeural representationFlavor perceptReward valueFlavor processingAffective valueOral somatosensationFood rewardInternal statesPerceptGustatory cortexCortexOrbital cortexRetronasal olfactionProcessingPleasantnessRewardEncodingSomatosensationRepresentation
2006
Central Gustatory Processing in Humans
Small DM. Central Gustatory Processing in Humans. Advances In Oto-Rhino-Laryngology 2006, 63: 191-220. PMID: 16733340, DOI: 10.1159/000093761.Peer-Reviewed Original Research
2005
Odor/taste integration and the perception of flavor
Small DM, Prescott J. Odor/taste integration and the perception of flavor. Experimental Brain Research 2005, 166: 345-357. PMID: 16028032, DOI: 10.1007/s00221-005-2376-9.Peer-Reviewed Original ResearchConceptsFlavor perceptionUnitary perceptionCross-modal sensory interactionsSensory inputVentral lateral prefrontal cortexParticular sensory characteristicsLateral prefrontal cortexPosterior parietal cortexMultiple sensory inputsAnterior cingulate cortexPerception of flavorAttentional allocationHeteromodal regionsNeural processesAnterior insulaFlavor processingFrontal operculumOrbitofrontal cortexPrefrontal cortexCingulate cortexFlavor of foodParietal cortexNeurophysiological studiesPerceptionSensory interaction
2004
Experience-Dependent Neural Integration of Taste and Smell in the Human Brain
Small DM, Voss J, Mak YE, Simmons KB, Parrish T, Gitelman D. Experience-Dependent Neural Integration of Taste and Smell in the Human Brain. Journal Of Neurophysiology 2004, 92: 1892-1903. PMID: 15102894, DOI: 10.1152/jn.00050.2004.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexPosterior parietal cortexOrbitofrontal cortexCaudal orbitofrontal cortexFrontal operculumPrefrontal cortexParietal cortexFlavor perceptionVentral lateral prefrontal cortexVentral insulaEvent-related fMRIVentrolateral prefrontal cortexLateral prefrontal cortexDistinct sensory inputsAnterior ventral insulaPerception of flavorUnimodal stimuliSuperadditive responsesNeural correlatesBrain responsesNeural responsesFlavor processingNeural suppressionOlfactory deliveryDorsal insula
1997
Flavor processing
Small D, Jones-Gotman M, Zatorre R, Petrides M, Evans A. Flavor processing. Neuroreport 1997, 8: 3913-3917. PMID: 9462465, DOI: 10.1097/00001756-199712220-00014.Peer-Reviewed Original ResearchConceptsCerebral blood flow changesBlood flow changesSignificant CBF decreasePositron emission tomographySecondary gustatoryCBF decreaseBasal forebrainCBF increaseOlfactory cortexFlavor processingPrimary gustatoryEmission tomographyGustatory stimuliIndependent presentationFlavor conditionFlow changesGustatoryUnpleasant stimuliIdentical stimuliOlfactorySimultaneous presentationPresentationStimuli