2015
Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum
Cosgrove KP, Veldhuizen MG, Sandiego CM, Morris ED, Small DM. Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum. Synapse 2015, 69: 195-202. PMID: 25664726, PMCID: PMC4411955, DOI: 10.1002/syn.21809.Peer-Reviewed Original ResearchConceptsBody mass indexPalatable food consumptionDorsal striatumMass indexBOLD responseReceptor availabilityRelationship of BMIFood consumptionPET studiesMagnetic resonance imaging studyPositron emission tomography studyBlood oxygen level-dependent (BOLD) responseDopamine D2/3 receptorsHigh-fat dietDopamine receptor levelsEmission tomography studiesFMRI studyResonance imaging studyFunctional magnetic resonance imaging studyLevel-dependent responsesReliable inverse relationshipHealthy weightD2/3 receptorsStriatal circuitryFat diet
2012
Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies
Tang D, Fellows L, Small D, Dagher A. Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies. Physiology & Behavior 2012, 106: 317-324. PMID: 22450260, DOI: 10.1016/j.physbeh.2012.03.009.Peer-Reviewed Original ResearchConceptsSmoking cuesOrbital frontal cortexNeutral cuesFood cuesVisual foodBlood oxygen level-dependent (BOLD) responseBrain regionsSimilar brain regionsBilateral orbital frontal cortexActivation likelihood estimationFrontal cortexFunctional MRI studyLevel-dependent responsesBrain imaging studiesNeuro-imaging studiesDrug cuesImaging studiesInsula activationSubjective cravingConditioned cuesIncentive salienceBrain responsesBilateral insulaBrain networksLeft amygdala