2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2019
Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2018
REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia
Hu C, Huber S, Latif SR, Santacana‐Laffitte G, Mojibian HR, Baldassarre LA, Peters DC. REPAIRit: Improving Myocardial Nulling and Ghosting Artifacts of 3D Navigator‐Gated Late Gadolinium Enhancement Imaging During Arrhythmia. Journal Of Magnetic Resonance Imaging 2018, 49: 688-699. PMID: 30252987, DOI: 10.1002/jmri.26284.Peer-Reviewed Original ResearchAssessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure
Seemann F, Baldassarre LA, Llanos‐Chea F, Gonzales RA, Grunseich K, Hu C, Sugeng L, Meadows J, Heiberg E, Peters DC. Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure. Physiological Reports 2018, 6: e13828. PMID: 30187654, PMCID: PMC6125607, DOI: 10.14814/phy2.13828.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementMagnetic resonance imagingPulmonary capillary wedge pressureLA late gadolinium enhancementCapillary wedge pressureTransthoracic echocardiographyDiastolic functionDiastolic parametersWedge pressureAtrial remodelingFilling pressureCardiovascular magnetic resonance imagingLeft atrial remodelingVentricular filling pressureAtrial late gadolinium enhancementLGE-magnetic resonance imagingDiastolic dysfunctionMedical chartsLA volumeAtrial fibrosisGadolinium enhancementResonance imagingPressure catheterizationLow interobserverEchocardiography
2016
T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1
Hu C, Sinusas AJ, Huber S, Thorn S, Stacy MR, Mojibian H, Peters DC. T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1. Journal Of Cardiovascular Magnetic Resonance 2016, 19: 63. PMID: 28821300, PMCID: PMC5563030, DOI: 10.1186/s12968-017-0375-1.Peer-Reviewed Original ResearchAlgorithmsAnimalsCardiomyopathiesComputer SimulationContrast MediaFeasibility StudiesFemaleFibrosisHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedModels, CardiovascularMonte Carlo MethodOrganometallic CompoundsPhantoms, ImagingPredictive Value of TestsReproducibility of ResultsSus scrofa
2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2013
Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order
Shaw JL, Knowles BR, Goldfarb JW, Manning WJ, Peters DC. Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order. Journal Of Magnetic Resonance Imaging 2013, 40: 119-125. PMID: 24105717, PMCID: PMC5036388, DOI: 10.1002/jmri.24340.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAlgorithmsAtrial FibrillationBody WaterContrast MediaFemaleGadoliniumHeart AtriaHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial StunningPreoperative CarePulmonary VeinsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSubtraction TechniqueConceptsWater-fat separationEvaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2012
Respiratory bellows‐gated late gadolinium enhancement of the left atrium
Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows‐gated late gadolinium enhancement of the left atrium. Journal Of Magnetic Resonance Imaging 2012, 38: 1210-1214. PMID: 23197465, PMCID: PMC3812253, DOI: 10.1002/jmri.23954.Peer-Reviewed Original ResearchConceptsRight inferior pulmonary veinLate gadolinium enhancementRight superior PVAtrial fibrillationGadolinium enhancementRespiratory compensationScar presenceInferior pulmonary veinNav gatingPresence of scarAtrial imagingSuperior PVBlinded gradingPulmonary veinsLeft atriumTrue scarsPatientsQuadrantScarImproved assessmentFibrillationAtrium
2010
Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging
Harrigan CJ, Peters DC, Gibson CM, Maron BJ, Manning WJ, Maron MS, Appelbaum E. Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging. Radiology 2010, 258: 128-33. PMID: 21045187, DOI: 10.1148/radiol.10090526.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementHypertrophic cardiomyopathyGadolinium enhancementExtent of LGEMean signal intensityCardiovascular magnetic resonance imagingLGE cardiovascular magnetic resonance imagingNormal remote myocardiumVisual assessmentMagnetic resonance imagingInternal Review BoardStudy patientsMean ageBland-Altman analysisLarge cohortRemote myocardiumBody weightMore weeksPatientsSignal intensityResonance imagingGadopentetate dimeglumineMore SDsMR imagingReview boardLate Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations
MENG J, PETERS DC, HSING JM, CHUANG ML, CHAN J, FISH A, JOSEPHSON ME, MANNING WJ. Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations. Pacing And Clinical Electrophysiology 2010, 33: 661-666. PMID: 20059713, DOI: 10.1111/j.1540-8159.2009.02671.x.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationCardiovascular magnetic resonance imagingAtrial fibrillationVein isolationLGE-CMRPost-pulmonary vein isolationLate gadolinium enhancement cardiovascular magnetic resonance imagingEnhancement cardiovascular magnetic resonance imagingFrequent imaging findingsLeft atrium cavityLate gadolinium enhancementMagnetic resonance imagingEsophageal positionImaging findingsEsophageal locationGadolinium enhancementHyperenhancementNoninvasive assessmentVertebral bodyResonance imagingClinical implicationsAblation siteLonger ablation timePatientsCardiac MR
2009
Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy
Han Y, Peters DC, Dokhan B, Manning WJ. Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy. Journal Of Magnetic Resonance Imaging 2009, 30: 967-972. PMID: 19856417, PMCID: PMC2862561, DOI: 10.1002/jmri.21953.Peer-Reviewed Original ResearchConceptsDCM patientsDiffuse fibrosisCardiovascular magnetic resonance studyLGE CMR imagesCardiomyopathy patientsHealthy controlsHealthy subjectsLGE-CMRHeart ratePatientsFibrosisOptimal inversion timeBloodMyocardiumMyocardium contrastInversion timeShort differencesBlood signalBlood SNRDCMOptimal timeLower CNRLeft ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR
Peters DC, Appelbaum EA, Nezafat R, Dokhan B, Han Y, Kissinger KV, Goddu B, Manning WJ. Left ventricular infarct size, peri‐infarct zone, and papillary scar measurements: A comparison of high‐resolution 3D and conventional 2D late gadolinium enhancement cardiac MR. Journal Of Magnetic Resonance Imaging 2009, 30: 794-800. PMID: 19787731, PMCID: PMC2981352, DOI: 10.1002/jmri.21897.Peer-Reviewed Original ResearchAssociation of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Appelbaum E, Abraham JM, Pride YB, Harrigan CJ, Peters DC, Biller LH, Manning WJ, Gibson CM. Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. American Heart Journal 2009, 158: 84-91. PMID: 19540396, DOI: 10.1016/j.ahj.2009.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngioplasty, Balloon, CoronaryCardiac VolumeContrast MediaCoronary AngiographyCoronary CirculationElectrocardiographyEndocardiumFemaleGadolinium DTPAHeart VentriclesHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionMyocardial Reperfusion InjuryMyocardiumPericardiumPrognosisSignal Processing, Computer-AssistedThrombolytic TherapyTreatment OutcomeConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionMyocardial perfusion gradeInfarct border zoneMyocardial Infarction (TIMI) myocardial perfusion gradeElevation myocardial infarctionPercutaneous coronary interventionInfarct sizePerfusion gradeMyocardial perfusionInfarct surface areaCoronary interventionMyocardial infarctionInfarct architectureCardiovascular magnetic resonance measuresNormal epicardial flowDays of presentationMagnetic resonance measuresCardiovascular magnetic resonanceImpaired thrombolysisEpicardial flowThrombolysisPatientsPerfusionTMPGRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring
2008
Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse
Han Y, Peters DC, Salton CJ, Bzymek D, Nezafat R, Goddu B, Kissinger KV, Zimetbaum PJ, Manning WJ, Yeon SB. Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse. JACC Cardiovascular Imaging 2008, 1: 294-303. PMID: 19356441, DOI: 10.1016/j.jcmg.2008.01.013.Peer-Reviewed Original ResearchMeSH KeywordsArrhythmias, CardiacCase-Control StudiesContrast MediaEchocardiography, DopplerFibrosisGadolinium DTPAHumansImaging, Three-DimensionalMagnetic Resonance Imaging, CineMitral ValveMitral Valve ProlapsePapillary MusclesPredictive Value of TestsProspective StudiesSensitivity and SpecificityConceptsMitral valve prolapseComplex ventricular arrhythmiasMVP patientsMitral annular diameterValve prolapseControl subjectsPapillary musclesTransthoracic echocardiographyVentricular arrhythmiasAnnular diameterDiagnostic criteriaCardiovascular magnetic resonance characterizationCommon valvular heart diseaseLeft ventricular outflow tractCMR diagnostic criteriaSubgroup of patientsValvular heart diseaseVentricular outflow tractGold standardLate gadolinium enhancementCardiovascular magnetic resonanceMitral valve morphologyValuable imaging toolClinical gold standardControl patients
2005
Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size.
Syed MA, Peters DC, Rashid H, Arai AE. Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size. Journal Of Cardiovascular Magnetic Resonance 2005, 7: 355-60. PMID: 15881514, DOI: 10.1081/jcmr-200053458.Peer-Reviewed Original ResearchConceptsPulmonary vein ostial diametersMagnetic resonance angiographyPulmonary veinsCine CMROstial diameterNormal volunteersResonance angiographyAtrial fibrillation ablation proceduresAtrial fibrillation patientsPulmonary vein diameterCardiac magnetic resonanceCine cardiac magnetic resonanceThree-dimensional magnetic resonance angiographyContrast-enhanced 3D MRAFibrillation patientsAtrial fibrillationVein diameterAblation proceduresAnatomical depictionPatientsT scannerAngiographyCine MRICMRVein
2003
Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine
Dick AJ, Guttman MA, Raman VK, Peters DC, Pessanha BS, Hill JM, Smith S, Scott G, McVeigh ER, Lederman RJ. Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine. Circulation 2003, 108: 2899-2904. PMID: 14656911, PMCID: PMC1325104, DOI: 10.1161/01.cir.0000095790.28368.f9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiac CatheterizationComputer SystemsContrast MediaFeasibility StudiesFerrosoferric OxideGadolinium DTPAImaging, Three-DimensionalIronMagnetic Resonance ImagingMesenchymal Stem Cell TransplantationMicroscopy, FluorescenceMicrospheresMyocardial InfarctionOxidesPhantoms, ImagingSafetySwine, MiniatureTransplantation, HomologousUndersampled projection reconstruction for active catheter imaging with adaptable temporal resolution and catheter‐only views
Peters DC, Lederman RJ, Dick AJ, Raman VK, Guttman MA, Derbyshire JA, McVeigh ER. Undersampled projection reconstruction for active catheter imaging with adaptable temporal resolution and catheter‐only views. Magnetic Resonance In Medicine 2003, 49: 216-222. PMID: 12541240, PMCID: PMC2396305, DOI: 10.1002/mrm.10390.Peer-Reviewed Original Research