2023
Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis
Feher A, Miller E, Peters D, Mojibian H, Sinusas A, Hinchcliff M, Baldassarre L. Impaired left-ventricular global longitudinal strain by feature-tracking cardiac MRI predicts mortality in systemic sclerosis. Rheumatology International 2023, 43: 849-858. PMID: 36894756, DOI: 10.1007/s00296-023-05294-6.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementLV-GLSSystemic sclerosisWorse survivalClinical indicationsImpaired left ventricular global longitudinal strainLeft ventricular global longitudinal strainPresence of LGECMR strainLV cardiac indexWorse LV-GLSLV ejection fractionCox regression analysisGlobal longitudinal strainLV cardiac outputGlobal radialCardiac indexOverall survivalRetrospective cohortEjection fractionPrognostic valueAdverse outcomesCardiac outputGadolinium enhancementRV strain
2019
Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2010
Circumferential myocardial strain in cardiomyopathy with and without left bundle branch block
Han Y, Chan J, Haber I, Peters DC, Zimetbaum PJ, Manning WJ, Yeon SB. Circumferential myocardial strain in cardiomyopathy with and without left bundle branch block. Journal Of Cardiovascular Magnetic Resonance 2010, 12: 2. PMID: 20047696, PMCID: PMC2806866, DOI: 10.1186/1532-429x-12-2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBundle-Branch BlockCardiac Pacing, ArtificialCardiomyopathiesCase-Control StudiesFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionObserver VariationPatient SelectionPredictive Value of TestsReproducibility of ResultsStroke VolumeSystoleVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft bundle branch blockNon-LBBB groupBundle branch blockCardiovascular magnetic resonanceCircumferential strainLBBB patientsVentricular levelBranch blockCardiomyopathy patientsHealthy controlsVentricular slicesContraction patternLeft ventricular contraction patternAdvanced heart failure patientsBackgroundCardiac resynchronization therapyDepressed systolic functionHeart failure patientsNon-LBBB patientsVentricular contraction patternCircumferential myocardial strainMyocardial circumferential strainNon-invasive parametersSystolic circumferential strainMid-ventricular levelCircumferential strain analysis
2009
Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy
Han Y, Peters DC, Dokhan B, Manning WJ. Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy. Journal Of Magnetic Resonance Imaging 2009, 30: 967-972. PMID: 19856417, PMCID: PMC2862561, DOI: 10.1002/jmri.21953.Peer-Reviewed Original ResearchConceptsDCM patientsDiffuse fibrosisCardiovascular magnetic resonance studyLGE CMR imagesCardiomyopathy patientsHealthy controlsHealthy subjectsLGE-CMRHeart ratePatientsFibrosisOptimal inversion timeBloodMyocardiumMyocardium contrastInversion timeShort differencesBlood signalBlood SNRDCMOptimal timeLower CNR