2010
Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults
Dunne DW, Shaw A, Bockenstedt LK, Allore HG, Chen S, Malawista SE, Leng L, Mizue Y, Piecychna M, Zhang L, Towle V, Bucala R, Montgomery RR, Fikrig E. Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults. PLOS ONE 2010, 5: e11343. PMID: 20596538, PMCID: PMC2893205, DOI: 10.1371/journal.pone.0011343.Peer-Reviewed Original ResearchConceptsNon-immunosuppressed adultsMIF levelsImmunosuppressive medicationsAutoimmune diseasesIL-8Cytokine productionMonocyte Toll-like receptor (TLR) expressionInnate immunityToll-like receptor expressionEnhanced innate immune responseAltered host immunityAutoimmune disease groupDownstream cytokine productionNon-immunosuppressed individualsUnderlying autoimmune diseaseFeatures of patientsHuman peripheral blood monocytesTLR4 surface expressionCytokine IL-8Number of patientsSurface expressionPeripheral blood monocytesInnate immune responseRisk of infectionImmunosuppressed adults
2006
Comparative epidemiology of Chlamydia trachomatis infection among men attending sexually transmitted disease clinics with and without indication for testing
Rowhani-Rahbar A, Niccolai LM, Dunne DW, Green S, Jenkins H, Khoshnood K. Comparative epidemiology of Chlamydia trachomatis infection among men attending sexually transmitted disease clinics with and without indication for testing. International Journal Of STD & AIDS 2006, 17: 453-458. PMID: 16820074, DOI: 10.1258/095646206777689143.Peer-Reviewed Original ResearchConceptsC. trachomatis infectionChlamydia trachomatis infectionTrachomatis infectionRoutine reproductive health careDifferent clinical settingsReproductive health careHealth care providersRisk of infectionElectronic medical recordsGroup of menSTD clinicDisease clinicMale patientsMedical recordsRisk factorsPrior historyClinical settingInfectionComparative epidemiologyHealth careYoung menMenClinicEpidemiologyIndications