2024
Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities
Katz M, Mszar R, Grimshaw A, Gunderson C, Onuma O, Lu Y, Spatz E. Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities. JAMA Network Open 2024, 7: e2356070. PMID: 38353950, PMCID: PMC10867699, DOI: 10.1001/jamanetworkopen.2023.56070.Peer-Reviewed Original ResearchConceptsDigital health interventionsHealth disparitiesHealth interventionsSystematic reviewSystolic BPSocial determinants of healthHypertension managementCommunity health workersFactors associated with cardiovascular diseaseDeterminants of healthLeveraging digital healthRemote BP monitoringDigital health technologiesStandard care groupMeta-analysisBlood pressureDiastolic BPPreferred Reporting ItemsControl groupSystolic BP changeBaseline to 6Random-effects modelSkilled nursingCultural tailoringSocial determinants
2023
Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseEffects of exerciseFatty liver diseaseHistological outcomesLiver histologyLiver diseaseClinical trialsHistological endpointsSystematic reviewSignificant histopathological improvementNAFLD activity scoreImpact of exerciseIndependent effectsRandom-effects modelSystematic literature searchHistopathological improvementExercise interventionActivity scoreClinical endpointsPooled estimatesMeta-AnalysisTotal participantsLiterature searchComparison groupA Multicenter Observational Study Comparing Virtual with In-Person Morning Reports during the COVID-19 Pandemic
Bradley J, Redinger J, Tuck M, Sweigart J, Smeraglio A, Mitchell C, Laudate J, Kwan B, Jagannath A, Heppe D, Guidry M, Ehlers E, Cyr J, Cornia P, Chun J, Caputo L, Arundel C, Albert T, Gunderson C. A Multicenter Observational Study Comparing Virtual with In-Person Morning Reports during the COVID-19 Pandemic. Southern Medical Journal 2023, 116: 745-749. PMID: 37657781, DOI: 10.14423/smj.0000000000001597.Peer-Reviewed Original ResearchConceptsProspective observational studyCoronavirus disease 2019 (COVID-19) pandemicMorning reportDisease 2019 pandemicCOVID-19 pandemicInternal medicine residency programsMedicine residency programsSingle hospitalObservational studyCase-based presentationsPatient diagnosisMultiple hospitalsMarked increaseNumber of slidesCOVID-19HospitalMorning report formatReport formatMore participantsResidency programsReportPandemic restrictionsPerson reportsAttendingsProgram directorsEstimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis
Carey G, Holleck J, Alshaeba S, Jayakrishnan R, Gordon K, Grimshaw A, Gunderson C. Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2023, 78: 1150-1159. PMID: 36964648, DOI: 10.1093/jac/dkad078.Peer-Reviewed Original ResearchConceptsCommon infectious syndromesEmpirical antibioticsPrevalence of MRSAInfectious syndromesMRSA infectionIll patientsMortality rateSystematic reviewAbsolute mortality benefitAnti-MRSA therapyEmpirical antibiotic coverageLow-risk infectionsSoft tissue infectionsUrinary tract infectionAbsolute risk reductionMethicillin-resistant Staphylococcus aureusCatheter-related infectionsStudy of patientsBaseline mortality ratesSystematic literature searchWeb of ScienceMRSA coverageAntibiotic coverageEmpirical antimicrobialsMortality benefitBurden of bone disease in chronic pancreatitis: A systematic review and meta-analysis
Chhoda A, Hernandez-Woodbine M, Addo N, Nasir S, Grimshaw A, Gunderson C, Ahmed A, Freedman S, Sheth S. Burden of bone disease in chronic pancreatitis: A systematic review and meta-analysis. World Journal Of Gastroenterology 2023, 29: 1374-1394. PMID: 36925454, PMCID: PMC10011962, DOI: 10.3748/wjg.v29.i8.1374.Peer-Reviewed Original ResearchConceptsPrevalence of osteopeniaChronic pancreatitisFragility fracturesBone diseaseCP patientsClinical featuresPooled prevalenceSystematic reviewBaseline clinical featuresSignificant bone diseasePrevalence of osteoporosisBody mass indexCause of morbidityBone mineralization parametersRandom-effects modelPaucity of dataWeb of SciencePERT useSmoking exposureSystemic inflammationTherapy useMass indexTrue burdenCochrane LibraryMean ageWhat internal medicine attendings talk about at morning report: a multicenter study
Redinger J, Heppe D, Albert T, Cornia P, Gordon K, Arundel C, Bradley J, Caputo L, Chun J, Cyr J, Ehlers E, Guidry M, Jagannath A, Kwan B, Laudate J, Mitchell C, Smeraglio A, Sweigart J, Tuck M, Gunderson C. What internal medicine attendings talk about at morning report: a multicenter study. BMC Medical Education 2023, 23: 84. PMID: 36732763, PMCID: PMC9893973, DOI: 10.1186/s12909-023-04057-y.Peer-Reviewed Original Research
2022
Overdiagnosis of cellulitis
Gunderson C, Anderson M. Overdiagnosis of cellulitis. Journal Of Hospital Medicine 2022, 18: 281-282. PMID: 36510698, DOI: 10.1002/jhm.13024.Commentaries, Editorials and LettersEvidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis
Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Tanoue L, Bastian LA. Evidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis. Journal Of General Internal Medicine 2022, 37: 3731-3738. PMID: 35838866, PMCID: PMC9585128, DOI: 10.1007/s11606-022-07613-2.Peer-Reviewed Original ResearchConceptsLung cancer screeningLCS participationLung cancer mortalityScreening ratesWhite patientsSystematic reviewCancer mortalityPatient populationRacial disparitiesPatient studiesLung cancer screening processAllied Health Literature databasesLow-dose chestHigh-risk individualsMethodsA systematic reviewCancer screening processFull-text reviewTitles/abstractsWeb of ScienceBlack patientsDatabase inceptionCancer screeningClinical trialsInclusion criteriaProvider awarenessA Comparative Study of Scripted versus Unscripted Morning Reports: Results from a Prospective Multicenter Study
Jagannath AD, Kwan B, Heppe DB, Beard AS, Cornia PB, Albert T, Lankarani-Fard A, Bradley JM, Guidry MM, Tuck M, Fletcher KE, Gunderson CG. A Comparative Study of Scripted versus Unscripted Morning Reports: Results from a Prospective Multicenter Study. Southern Medical Journal 2022, 115: 400-403. PMID: 35777743, DOI: 10.14423/smj.0000000000001411.Peer-Reviewed Original ResearchBenefit of Extended Surveillance of Low-Risk Pancreatic Cysts After 5-Year Stability: A Systematic Review and Meta-Analysis
Chhoda A, Singh S, Sheth AH, Grimshaw AA, Gunderson C, Sharma P, Kunstman JW, Sharma A, Ahuja N, Gonda TA, Farrell JJ. Benefit of Extended Surveillance of Low-Risk Pancreatic Cysts After 5-Year Stability: A Systematic Review and Meta-Analysis. Clinical Gastroenterology And Hepatology 2022, 21: 1430-1446. PMID: 35568304, DOI: 10.1016/j.cgh.2022.04.025.Peer-Reviewed Original ResearchConceptsDisease-specific mortalityAdvanced neoplasiaBD-IPMNsExtended surveillancePooled incidenceWorrisome featuresSystematic reviewIntraductal papillary mucinous neoplasmHigh-grade dysplasiaPapillary mucinous neoplasmHigh-quality studiesRandom-effects modelWarrants further investigationWeb of ScienceNeoplasia incidenceWarrants further explorationSurvival benefitCochrane LibraryMucinous neoplasmsPancreatic cancerPancreatic cystsSurveillance periodEligible studiesOvid MEDLINELower incidenceOverstating inpatient deaths due to medical error erodes trust in healthcare and the patient safety movement
Gunderson CG, Rodwin BA. Overstating inpatient deaths due to medical error erodes trust in healthcare and the patient safety movement. Journal Of Hospital Medicine 2022, 17: 399-402. PMID: 35535945, DOI: 10.1002/jhm.2768.Peer-Reviewed Original Research
2021
Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis
Chhoda A, Vodusek Z, Wattamwar K, Mukherjee E, Gunderson C, Grimshaw A, Sharma A, Ahuja N, Kastrinos F, Farrell JJ. Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis. Gastroenterology 2021, 162: 786-798. PMID: 34813861, DOI: 10.1053/j.gastro.2021.11.021.Peer-Reviewed Original ResearchConceptsLate-stage PDACPancreatic ductal adenocarcinomaHigh-risk individualsHigh-grade precursorsCumulative incidenceAdvanced neoplasiaLate-stage pancreatic cancerTiming of presentationRandom-effects modelWeb of ScienceClinicoradiologic factorsClinicoradiologic featuresSurveillance imagingCochrane LibraryPancreatic cancerDuctal adenocarcinomaPancreatic morphologySurveillance studyFunnel plotLesion sitePDAC stagesSurveillance adherenceSystematic reviewMeta-AnalysisSignificant associationRacial Differences in Adherence to Lung Cancer Screening Follow-up A Systematic Review and Meta-analysis
Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Cain H, Tanoue L, Bastian LA. Racial Differences in Adherence to Lung Cancer Screening Follow-up A Systematic Review and Meta-analysis. CHEST Journal 2021, 161: 266-275. PMID: 34390706, DOI: 10.1016/j.chest.2021.07.2172.Peer-Reviewed Original ResearchConceptsLung cancer screeningLung cancer mortalityCancer mortalityCancer screeningLow adherenceSystematic reviewAnnual lung cancer screeningLung cancer mortality benefitLow-dose chest CTEligible black patientsAllied Health Literature databasesA Systematic ReviewRate of adherenceHigh-risk individualsUnited States Preventive Services TaskforceFull-text reviewHealth Literature databasesWeb of ScienceLCS adherenceLCS participationBlack populationMortality benefitWhite patientsBlack patientsInitial screening resultsImproving the Quality of Inpatient Discharge Instructions: An Evaluation and Implementation of Best Practices
Rodwin BA, Bilan VP, Gunderson CG, Merchant NB. Improving the Quality of Inpatient Discharge Instructions: An Evaluation and Implementation of Best Practices. Southern Medical Journal 2021, 114: 445-449. PMID: 34345921, DOI: 10.14423/smj.0000000000001284.Peer-Reviewed Original ResearchRisk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis
Holleck JL, Roberts AE, Marhoffer EA, Grimshaw AA, Gunderson CG. Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis. Journal Of Hospital Medicine 2021, 16: 489-494. PMID: 34328838, DOI: 10.12788/jhm.3655.Peer-Reviewed Original ResearchConceptsSevere gastrointestinal side effectsGastrointestinal side effectsIntestinal necrosisHazard ratioSide effectsComposite outcomeOdds ratioSodium polystyrene sulfonateSystematic reviewSevere gastrointestinal adverse eventsGastrointestinal adverse eventsPooled hazard ratioRisk of biasPooled odds ratioCase-control studyPrior systematic reviewsSystematic literature searchAdverse eventsAlternative medicationsCochrane LibraryDatabase inceptionClinical trialsNecrosis rateInclusion criteriaPotential confoundingEvaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis
Chhoda A, Dawod S, Grimshaw A, Gunderson C, Mahadev S. Evaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis. Gastrointestinal Endoscopy 2021, 94: 890-901.e8. PMID: 34245751, DOI: 10.1016/j.gie.2021.07.002.Peer-Reviewed Original ResearchConceptsCommon bile duct dilationBile duct dilationAsymptomatic patientsBiliary dilationDiagnostic yieldCBD dilationDuct dilationEUS evaluationSystematic reviewHealth resource utilizationInverse variance methodRandom-effects modelCost-effectiveness analysisRadiologic evidenceBenign etiologyMalignant etiologyFrequent indicationOvid EmbaseAsymptomatic individualsCochrane LibraryMalignant pathologyOvid MEDLINEFurther interventionPatientsGoogle ScholarInternal Medicine Residents’ Perceptions of Virtual Morning Report: a Multicenter Survey
Albert TJ, Bradley J, Starks H, Redinger J, Arundel C, Beard A, Caputo L, Chun J, Gunderson CG, Heppe D, Jagannath A, Kent K, Krug M, Laudate J, Palaniappan V, Pensiero A, Sargsyan Z, Sladek E, Tuck M, Cornia PB. Internal Medicine Residents’ Perceptions of Virtual Morning Report: a Multicenter Survey. Journal Of General Internal Medicine 2021, 37: 1422-1428. PMID: 34173198, PMCID: PMC8231750, DOI: 10.1007/s11606-021-06963-7.Peer-Reviewed Original ResearchConceptsMorning reportCOVID-19 pandemicVirtual platformUnique educational benefitsAudience response systemResidency programsGraduate Medical EducationIM residency programsInternal medicine residency programsInternal Medicine Residents’ PerceptionsTeaching strategiesLearning environmentEducational experienceOverall educationEducational benefitsEducational formatMedical educationMedicine residency programsVirtual formatThird-year residentsEducational conferencesMain MeasuresTheMost respondentsTraining programChat boxInternal Medicine Residents’ Perceptions of Morning Report: a Multicenter Survey
Albert TJ, Redinger J, Starks H, Bradley J, Gunderson CG, Heppe D, Kent K, Krug M, Kwan B, Laudate J, Pensiero A, Raymond G, Sladek E, Sweigart JR, Cornia PB. Internal Medicine Residents’ Perceptions of Morning Report: a Multicenter Survey. Journal Of General Internal Medicine 2021, 36: 647-653. PMID: 33443704, PMCID: PMC7947099, DOI: 10.1007/s11606-020-06351-7.Peer-Reviewed Original ResearchConceptsMorning reportLearning environmentClinical reasoningLearner-centric pedagogyInclusive learning environmentsEvidence-based teachingResident duty hour limitationsGraduate Medical EducationMultiple-choice questionsHigh-quality casesInternal Medicine Residents’ PerceptionsTeaching strategiesDuty hour limitationsMedical educatorsEducational activitiesLevel of trainingLittle contemporary evidenceEducational topicsMedical educationMedical studentsPARTICIPANTSInternal medicine residentsEducational conferencesMain MeasuresTheResidency programsTeaching
2020
The Association Between Prescribed Opioid Receipt and Community-Acquired Pneumonia in Adults: a Systematic Review and Meta-analysis
Steffens C, Sung M, Bastian LA, Edelman EJ, Brackett A, Gunderson CG. The Association Between Prescribed Opioid Receipt and Community-Acquired Pneumonia in Adults: a Systematic Review and Meta-analysis. Journal Of General Internal Medicine 2020, 35: 3315-3322. PMID: 32885375, PMCID: PMC7661588, DOI: 10.1007/s11606-020-06155-9.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaRisk of CAPOpioid receiptCase-control studyRisk factorsIncidence of CAPNewcastle-Ottawa Quality Assessment ScaleSystematic reviewCochrane Central RegisterImpact of opioidsChronic medical conditionsPost-operative patientsQuality Assessment ScaleCurrent opioid epidemicSystematic literature searchWeb of SciencePublic health crisisRespiratory depressionCentral RegisterCohort studyCough suppressionOpioid useControlled TrialsRespiratory infectionsDatabase inceptionThe Impact of Medications for Opioid Use Disorder on Hepatitis C Incidence Among Incarcerated Persons A Systematic Review
Seval N, Wurcel A, Gunderson CG, Grimshaw A, Springer SA. The Impact of Medications for Opioid Use Disorder on Hepatitis C Incidence Among Incarcerated Persons A Systematic Review. Infectious Disease Clinics Of North America 2020, 34: 559-584. PMID: 32782102, PMCID: PMC7437982, DOI: 10.1016/j.idc.2020.06.011.Peer-Reviewed Original Research