2024
Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study
Holleck J, Han L, Skanderson M, Bastian L, Gunderson C, Brandt C, Perkal M, Chang J, Akgün K. Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study. Journal Of General Internal Medicine 2024, 1-7. PMID: 39103605, DOI: 10.1007/s11606-024-08979-1.Peer-Reviewed Original ResearchAdjusted odds ratiosSodium zirconium cyclosilicateU.S. Department of Veterans Affairs healthcare systemDepartment of Veterans Affairs healthcare systemVA Corporate Data WarehouseVeterans Affairs Healthcare SystemCorporate Data WarehousePotassium bindersHospitalized patientsGI eventsHealthcare systemOdds ratioAdverse GI eventsSodium polystyrene sulfonateNational studyPotassium-binding drugsComparative riskAdverse gastrointestinal eventsGI adverse eventsTreatment of hyperkalemiaZirconium cyclosilicateGastrointestinal eventsPatiromerAdverse events
2021
Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis
Holleck JL, Roberts AE, Marhoffer EA, Grimshaw AA, Gunderson CG. Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis. Journal Of Hospital Medicine 2021, 16: 489-494. PMID: 34328838, DOI: 10.12788/jhm.3655.Peer-Reviewed Original ResearchConceptsSevere gastrointestinal side effectsGastrointestinal side effectsIntestinal necrosisHazard ratioSide effectsComposite outcomeOdds ratioSodium polystyrene sulfonateSystematic reviewSevere gastrointestinal adverse eventsGastrointestinal adverse eventsPooled hazard ratioRisk of biasPooled odds ratioCase-control studyPrior systematic reviewsSystematic literature searchAdverse eventsAlternative medicationsCochrane LibraryDatabase inceptionClinical trialsNecrosis rateInclusion criteriaPotential confounding