2019
Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution
Balbuena‐Merle R, West FB, Tormey CA, Hendrickson JE. Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution. Transfusion 2019, 59: 1911-1915. PMID: 30865314, DOI: 10.1111/trf.15240.Peer-Reviewed Original ResearchConceptsGroup B patientsHemolytic transfusion reactionsDirect antiglobulin testB patientsTransfusion reactionsApheresis unitsBlood group B patientsRelapsed acute myeloid leukemiaAcute hemolytic transfusion reactionAnti-human globulin phaseHigh lactate dehydrogenaseAnti-human globulinAcute myeloid leukemiaRecipient testingDonor testingRecipient variablesExtravascular hemolysisPlatelet transfusionsTransfusion recipientsAntibody screenHigh bilirubinPLT transfusionsAntiglobulin testBlood productsMyeloid leukemia
2018
Visualization of bacterial contamination in an apheresis platelet unit
Siddon AJ, Snyder EL, Tormey CA. Visualization of bacterial contamination in an apheresis platelet unit. Journal Of Clinical Apheresis 2018, 33: 671-672. PMID: 30242893, DOI: 10.1002/jca.21649.Peer-Reviewed Original Research
2017
The perils of storing thawed cryoprecipitate in the refrigerator
Bahar B, Cheng C, Baine IL, Tormey CA. The perils of storing thawed cryoprecipitate in the refrigerator. Transfusion 2017, 57: 2826-2827. PMID: 29226374, DOI: 10.1111/trf.14175.Peer-Reviewed Original ResearchIrradiation of Red Blood Cells and Alloimmunization
Tormey CA, Hendrickson JE. Irradiation of Red Blood Cells and Alloimmunization. Lab Medicine 2017, 48: 172-177. PMID: 28340248, DOI: 10.1093/labmed/lmx018.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Component TransfusionBlood PreservationCohort StudiesErythrocytesFemaleGamma RaysHumansIsoantibodiesMaleRadiationConceptsAlloimmunization rateRBC alloimmunization rateTime of transfusionRBC unit transfusionPostoperative bleedingRed blood cell damageRed blood cellsRBC transfusionCommon diagnosisImmunosuppressive disordersTransfusion recipientsBlood cell damageAnimal modelsStudy subjectsTransfusionControl groupRBC antigensAntibody screeningRBC unitsPatientsBlood cellsCell damageRBCsOxidative damageDiagnosis
2016
Modelling gas exchange during platelet storage without agitation
Torres R, Tormey CA. Modelling gas exchange during platelet storage without agitation. Vox Sanguinis 2016, 111: 445-448. PMID: 27864979, DOI: 10.1111/vox.12452.Peer-Reviewed Original ResearchFluid motion and shear forces in platelet storage bags with different modes of agitation
Torres R, Tormey CA, Stack G. Fluid motion and shear forces in platelet storage bags with different modes of agitation. Vox Sanguinis 2016, 111: 209-212. PMID: 27078040, PMCID: PMC4981547, DOI: 10.1111/vox.12409.Peer-Reviewed Original Research
2015
Riboflavin‐ultraviolet light pathogen reduction treatment does not impact the immunogenicity of murine red blood cells
Tormey CA, Santhanakrishnan M, Smith NH, Liu J, Marschner S, Goodrich RP, Hendrickson JE. Riboflavin‐ultraviolet light pathogen reduction treatment does not impact the immunogenicity of murine red blood cells. Transfusion 2015, 56: 863-872. PMID: 26643781, DOI: 10.1111/trf.13432.Peer-Reviewed Original ResearchConceptsWhite blood cellsFresh whole bloodPathogen reduction treatmentAlloimmune responseWhole bloodRBC antigensSyngeneic RBCsNegative direct antiglobulin testBlood cellsRBC antigen expressionRecipient alloimmune responsesDirect antiglobulin testMurine red blood cellsPathogen inactivation treatmentPosttransfusion RBC recoveryKEL RBCsRBC alloimmunizationImmunogenic neoantigensRed blood cellsAntiglobulin testBlood donorsImmune responseAntigen expressionHours posttransfusionHuman antigens
2014
Use of a Cytokine-Release Assay to Demonstrate Loss of Platelet Secretory Capacity During Blood Bank Processing and Storage
Tormey CA, Stack G. Use of a Cytokine-Release Assay to Demonstrate Loss of Platelet Secretory Capacity During Blood Bank Processing and Storage. Archives Of Pathology & Laboratory Medicine 2014, 138: 1481-7. PMID: 25357109, DOI: 10.5858/arpa.2013-0680-oa.Peer-Reviewed Original Research
2010
In vitro and in vivo evaluation of a whole blood platelet‐sparing leukoreduction filtration system
Snyder EL, Whitley P, Kingsbury T, Miripol J, Tormey CA. In vitro and in vivo evaluation of a whole blood platelet‐sparing leukoreduction filtration system. Transfusion 2010, 50: 2145-2151. PMID: 20497514, DOI: 10.1111/j.1537-2995.2010.02701.x.Peer-Reviewed Original ResearchMeSH KeywordsBlood DonorsBlood PreservationErythrocytesHumansLeukocyte Reduction ProceduresLeukocytesPlasmaPlatelet TransfusionConceptsRed blood cellsWhite blood cellsAutologous plateletsTransfusion productsBlood cellsAdverse clinical sequelaeCPD plasmaProduction of plateletsResidual white blood cellsClinical sequelaeDrug Administration requirementsHospital useVivo efficacyLeukoreduction filtersBlood centersStudy designVivo evaluationLR productsVivo characteristicsPlateletsRBC recoveryAdministration requirementsVitroSurvival ratioFDA guidelines
2009
Analysis of transfusion reactions associated with prestorage‐pooled platelet components
Tormey CA, Sweeney JD, Champion MH, Pisciotto PT, Snyder EL, Wu Y. Analysis of transfusion reactions associated with prestorage‐pooled platelet components. Transfusion 2009, 49: 1242-1247. PMID: 19389029, DOI: 10.1111/j.1537-2995.2009.02128.x.Peer-Reviewed Original ResearchConceptsRandom donor plateletsSingle-donor plateletsTransfusion reactionsPlatelet infusionTransfusion-related acute lung injuryCommon adverse eventsPLT productsAcute lung injuryTertiary care hospitalCases of sepsisAllergic transfusion reactionsTransfusion reaction ratesSignificant differencesAdverse eventsLung injuryCare hospitalVolume overloadFebrile reactionsChi-square analysisTotal infusionPlatelet componentsInfusionStudy designP-valuePlatelets