2024
Mixed-field ABO front typing as an early sign of disease recurrence in ABO-matched stem cell transplantation
Yurtsever N, Lee E, Pinatti L, Shah B, Tormey C, Siddon A. Mixed-field ABO front typing as an early sign of disease recurrence in ABO-matched stem cell transplantation. Immunohematology 2024, 40: 89-92. PMID: 39373301, DOI: 10.2478/immunohematology-2024-013.Peer-Reviewed Original ResearchConceptsStem cell transplantationCell transplantationDisease recurrenceMyeloid neoplasmsChimerism testingAllogeneic stem cell transplantationSigns of disease recurrenceIndicator of disease recurrenceDonor-recipient pairsABO antigen expressionGraft statusAntigen expressionFemale patientsPost-transplantationAllograft statusTransplantationABO typeRecurrenceClinical settingEarly signsNeoplasmsChimerismEarly indicatorABOEngraftment
2019
Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution
Balbuena‐Merle R, West FB, Tormey CA, Hendrickson JE. Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution. Transfusion 2019, 59: 1911-1915. PMID: 30865314, DOI: 10.1111/trf.15240.Peer-Reviewed Original ResearchConceptsGroup B patientsHemolytic transfusion reactionsDirect antiglobulin testB patientsTransfusion reactionsApheresis unitsBlood group B patientsRelapsed acute myeloid leukemiaAcute hemolytic transfusion reactionAnti-human globulin phaseHigh lactate dehydrogenaseAnti-human globulinAcute myeloid leukemiaRecipient testingDonor testingRecipient variablesExtravascular hemolysisPlatelet transfusionsTransfusion recipientsAntibody screenHigh bilirubinPLT transfusionsAntiglobulin testBlood productsMyeloid leukemiaTransfusion-related red blood cell alloantibodies: induction and consequences
Tormey CA, Hendrickson JE. Transfusion-related red blood cell alloantibodies: induction and consequences. Blood 2019, 133: 1821-1830. PMID: 30808636, PMCID: PMC6484385, DOI: 10.1182/blood-2018-08-833962.Peer-Reviewed Original ResearchMeSH KeywordsABO Blood-Group SystemBlood Group IncompatibilityErythrocyte TransfusionErythrocytesHumansIsoantibodiesTransfusion ReactionConceptsTransfusion recipientsBlood donorsPreventative strategiesBlood product exposureCompatible RBC unitsRBC alloantibody formationHemolytic transfusion reactionsDevelopment of alloantibodiesAdaptive immune factorsJudicious transfusionRBC alloimmunizationImmunomodulatory therapyAlloantibody formationBlood transfusionRBC alloantibodiesRecipient variablesFuture pregnanciesImmune factorsTransfusion reactionsBlood productsHemolytic diseaseFuture transfusionsHuman studiesTransfusionAlloantibodies
2016
Bridging channel dendritic cells induce immunity to transfused red blood cells
Calabro S, Gallman A, Gowthaman U, Liu D, Chen P, Liu J, Krishnaswamy JK, Nascimento MS, Xu L, Patel SR, Williams A, Tormey CA, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE, Stowell SR, Eisenbarth SC. Bridging channel dendritic cells induce immunity to transfused red blood cells. Journal Of Experimental Medicine 2016, 213: 887-896. PMID: 27185856, PMCID: PMC4886363, DOI: 10.1084/jem.20151720.Peer-Reviewed Original ResearchMeSH KeywordsABO Blood-Group SystemAnimalsB-LymphocytesDendritic CellsErythrocyte TransfusionGalactosyltransferasesMiceMice, TransgenicPhagocytosisSpleenT-LymphocytesConceptsSplenic dendritic cellsDendritic cellsRBC transfusionT cellsImmune responseRed blood cell transfusionBlood cell transfusionT cell primingConventional dendritic cellsDetrimental immune responsesB cell responsesNaive T cellsT cell helpMurine transfusion modelRBC transfusion supportTime of transfusionRBC alloantigensCell transfusionDC subsetsAllogeneic RBCsRed blood cellsRenal failureTransfusion supportMajor complicationsCell priming
2008
Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure
Tormey CA, Stack G. Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure. Vox Sanguinis 2008, 95: 232-235. PMID: 19121188, DOI: 10.1111/j.1423-0410.2008.01085.x.Peer-Reviewed Original ResearchMeSH KeywordsABO Blood-Group SystemAgedBlood Group IncompatibilityErythrocyte TransfusionHemolysisHumansLiver FailureMaleTime FactorsConceptsABO-incompatible red blood cell (RBC) transfusionsRed blood cell transfusionBlood cell transfusionFresh frozen plasmaCell transfusionHepatic failureDelayed Haemolytic Transfusion ReactionAnamnestic antibody responseLow complement levelsHaemolytic transfusion reactionsOnset of haemolysisFirst transfusionRBC transfusionComplement levelsIncompatible transfusionsAntibody responseAntibody titresHepatic diseaseTransfusion reactionsIntravascular haemolysisTransfusionPatientsRBC unitsB RBCsHaemolysis