2019
Transfusion-related red blood cell alloantibodies: induction and consequences
Tormey CA, Hendrickson JE. Transfusion-related red blood cell alloantibodies: induction and consequences. Blood 2019, 133: 1821-1830. PMID: 30808636, PMCID: PMC6484385, DOI: 10.1182/blood-2018-08-833962.Peer-Reviewed Original ResearchConceptsTransfusion recipientsBlood donorsPreventative strategiesBlood product exposureCompatible RBC unitsRBC alloantibody formationHemolytic transfusion reactionsDevelopment of alloantibodiesAdaptive immune factorsJudicious transfusionRBC alloimmunizationImmunomodulatory therapyAlloantibody formationBlood transfusionRBC alloantibodiesRecipient variablesFuture pregnanciesImmune factorsTransfusion reactionsBlood productsHemolytic diseaseFuture transfusionsHuman studiesTransfusionAlloantibodies
2016
Understanding red blood cell alloimmunization triggers
Hendrickson JE, Tormey CA. Understanding red blood cell alloimmunization triggers. Hematology 2016, 2016: 446-451. PMID: 27913514, PMCID: PMC6142457, DOI: 10.1182/asheducation-2016.1.446.Peer-Reviewed Original ResearchConceptsRBC alloimmunizationRed blood cellsRisk factorsBlood cellsWhite blood cellsBlood group antigensPregnancy outcomesAlloantibody formationRBC alloantibodiesRBC transfusionRecipient factorsTransfusion safetyAlloimmunizationAnimal modelsHuman studiesPrevention strategiesDonor plasmaDanger signalsParticular antigenGroup antigensAntigenTransfusionPregnancyNonrespondersCells
2014
Red Blood Cell Alloimmunization Mitigation Strategies
Hendrickson JE, Tormey CA, Shaz BH. Red Blood Cell Alloimmunization Mitigation Strategies. Transfusion Medicine Reviews 2014, 28: 137-144. PMID: 24928468, DOI: 10.1016/j.tmrv.2014.04.008.Peer-Reviewed Original ResearchConceptsHemolytic transfusion reactionsRBC alloantibodiesRBC alloimmunizationTransfusion reactionsImmune systemRed blood cell alloantibodiesCompatible RBC unitsRBC alloimmunization rateTransfusion-associated morbidityRecipient's immune systemTransfusion-associated deathForms of anemiaAlloimmunization rateAntigen exposureSignificant morbidityTransfusion recipientsHemolytic diseaseAlloantibodiesHuman studiesAnimal studiesDanger signalsAnimal dataMorbidityAlloimmunizationRBC units