2019
Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution
Balbuena‐Merle R, West FB, Tormey CA, Hendrickson JE. Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution. Transfusion 2019, 59: 1911-1915. PMID: 30865314, DOI: 10.1111/trf.15240.Peer-Reviewed Original ResearchConceptsGroup B patientsHemolytic transfusion reactionsDirect antiglobulin testB patientsTransfusion reactionsApheresis unitsBlood group B patientsRelapsed acute myeloid leukemiaAcute hemolytic transfusion reactionAnti-human globulin phaseHigh lactate dehydrogenaseAnti-human globulinAcute myeloid leukemiaRecipient testingDonor testingRecipient variablesExtravascular hemolysisPlatelet transfusionsTransfusion recipientsAntibody screenHigh bilirubinPLT transfusionsAntiglobulin testBlood productsMyeloid leukemiaTransfusion-related red blood cell alloantibodies: induction and consequences
Tormey CA, Hendrickson JE. Transfusion-related red blood cell alloantibodies: induction and consequences. Blood 2019, 133: 1821-1830. PMID: 30808636, PMCID: PMC6484385, DOI: 10.1182/blood-2018-08-833962.Peer-Reviewed Original ResearchConceptsTransfusion recipientsBlood donorsPreventative strategiesBlood product exposureCompatible RBC unitsRBC alloantibody formationHemolytic transfusion reactionsDevelopment of alloantibodiesAdaptive immune factorsJudicious transfusionRBC alloimmunizationImmunomodulatory therapyAlloantibody formationBlood transfusionRBC alloantibodiesRecipient variablesFuture pregnanciesImmune factorsTransfusion reactionsBlood productsHemolytic diseaseFuture transfusionsHuman studiesTransfusionAlloantibodies
2014
Red Blood Cell Alloimmunization Mitigation Strategies
Hendrickson JE, Tormey CA, Shaz BH. Red Blood Cell Alloimmunization Mitigation Strategies. Transfusion Medicine Reviews 2014, 28: 137-144. PMID: 24928468, DOI: 10.1016/j.tmrv.2014.04.008.Peer-Reviewed Original ResearchConceptsHemolytic transfusion reactionsRBC alloantibodiesRBC alloimmunizationTransfusion reactionsImmune systemRed blood cell alloantibodiesCompatible RBC unitsRBC alloimmunization rateTransfusion-associated morbidityRecipient's immune systemTransfusion-associated deathForms of anemiaAlloimmunization rateAntigen exposureSignificant morbidityTransfusion recipientsHemolytic diseaseAlloantibodiesHuman studiesAnimal studiesDanger signalsAnimal dataMorbidityAlloimmunizationRBC units
2013
Limiting the Extent of a Delayed Hemolytic Transfusion Reaction With Automated Red Blood Cell Exchange
Tormey CA, Stack G. Limiting the Extent of a Delayed Hemolytic Transfusion Reaction With Automated Red Blood Cell Exchange. Archives Of Pathology & Laboratory Medicine 2013, 137: 861-4. PMID: 23721278, DOI: 10.5858/arpa.2012-0154-cr.Peer-Reviewed Original ResearchConceptsRed blood cell exchangeHemolytic transfusion reactionsDAT resultsTransfusion reactionsDirect antiglobulin test resultsCell exchangeIncompatible red blood cellsSymptoms of hemolysisRed blood cell unitsPositive antibody screenBlood group antibodiesAntigen-negative unitsAnamnestic increaseAntigen reexposureFurther hemolysisRed blood cellsAntibody screenGroup antibodiesPatient historyBlood cellsDHTRTransfusionHemolysisSymptomsCell units
2009
The persistence and evanescence of blood group alloantibodies in men
Tormey CA, Stack G. The persistence and evanescence of blood group alloantibodies in men. Transfusion 2009, 49: 505-512. PMID: 19040411, DOI: 10.1111/j.1537-2995.2008.02014.x.Peer-Reviewed Original ResearchConceptsBlood group alloantibodiesVeterans Affairs Medical CenterInitial negative testingTransfusion service recordsTransfusion-related alloimmunizationDuration of followHemolytic transfusion reactionsMonths of detectionFirst antibodyMale patientsTransfusion reactionsMedical CenterAlloantibodiesNegative testingAntibody detectionYear of inductionStudy designAntigenic specificityAntibodiesMilitary veteransPatientsMore yearsTwo-thirdsService recordsMen