2022
Studying the pathophysiology of tic disorders in animal models
Pittenger C. Studying the pathophysiology of tic disorders in animal models. International Review Of Movement Disorders 2022, 4: 39-61. DOI: 10.1016/bs.irmvd.2022.06.001.Peer-Reviewed Original Research
2015
Chapter 47 Animal Models of Tourette Syndrome and Obsessive-Compulsive Disorder
Pittenger C. Chapter 47 Animal Models of Tourette Syndrome and Obsessive-Compulsive Disorder. 2015, 747-764. DOI: 10.1016/b978-0-12-405195-9.00047-0.Peer-Reviewed Original ResearchObsessive-compulsive disorderTourette syndromeAnimal modelsCortico-basal ganglia circuitryAvailable pharmacological interventionsDysregulation of dopamineValid animal modelInhibitory transmissionSensory abnormalitiesSerotonergic modulationVocal ticsPharmacological interventionsLimited efficacyPrevalent diseaseNeuropsychiatric conditionsSyndromeModels of OCDComplex disorderNeurodevelopmental syndromeDisordersPathophysiologyNeurobiological processesPredictive validitySame circuitryBehavioral manipulation
2013
Tourette Syndrome and Tic Disorders
Williams K, Bloch M, State M, Pittenger C. Tourette Syndrome and Tic Disorders. 2013, 1048-1060. DOI: 10.1093/med/9780199934959.003.0079.Peer-Reviewed Original ResearchTourette syndromeTic disordersCortico-basal ganglia circuitryImmune-brain interactionPost-mortem findingsSubset of casesFunctional imaging studiesAttention deficit disorderObsessive-compulsive disorderVocal ticsDisorder pathophysiologySevere endImaging studiesDeficit disorderSpecific populationsDisordersSyndromeSensory phenomenaRecent findingsHeterogeneous genetic architecturePathophysiologyInterneuronsEtiologyAbnormalitiesFindings