The Effects of Platelet-Derived Growth Factor-BB on Healing of the Rabbit Medial Collateral Ligament
Hildebrand K, Woo S, Smith D, Allen C, Deie M, Taylor B, Schmidt C. The Effects of Platelet-Derived Growth Factor-BB on Healing of the Rabbit Medial Collateral Ligament. The American Journal Of Sports Medicine 1998, 26: 549-554. PMID: 9689377, DOI: 10.1177/03635465980260041401.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceAnimalsBecaplerminBiomechanical PhenomenaCell DivisionCollateral LigamentsDose-Response Relationship, DrugDrug CombinationsEpidermal Growth FactorExtracellular MatrixFibrin Tissue AdhesiveFibroblastsKnee InjuriesMaleMitogensPlatelet-Derived Growth FactorProto-Oncogene Proteins c-sisRabbitsRecombinant ProteinsRuptureTensile StrengthTransforming Growth Factor betaWeight-BearingWound HealingConceptsPlatelet-derived growth factor-BBMedial collateral ligament healingMedial collateral ligamentGrowth factor-BBPlatelet-derived growthCollateral ligamentGrowth factorFactor-BBLigament healingRight medial collateral ligamentFemur-medial collateral ligament-tibia complexRabbit medial collateral ligamentIndividual growth factorsHistologic evaluationHigh doseFibrin sealantControl groupHealing ligamentBiologic approachesFibroblast proliferationLigamentVitro workHealing tissueDosesHealing