Antimalarial Properties of Simplified Kalihinol Analogues
Daub ME, Prudhomme J, Mamoun C, Le Roch KG, Vanderwal CD. Antimalarial Properties of Simplified Kalihinol Analogues. ACS Medicinal Chemistry Letters 2017, 8: 355-360. PMID: 28337330, PMCID: PMC5346982, DOI: 10.1021/acsmedchemlett.7b00013.Peer-Reviewed Original ResearchNatural productsIsonitrile functional groupsPrevious total synthesisTotal synthesisFunctional groupsRepresentative compoundsReasonable stabilitySimple analogCompoundsAntimalarial propertiesAntimalarial activityAntimalarial agentsPotent activityAnaloguesInherent liabilitySclareolidePotent inhibitorSynthesisProductsScaffoldsKalihinolsStabilityAgentsProperties