2022
Alcohol and cannabis co‐use and longitudinal gray matter volumetric changes in early and late adolescence
Luo X, Yang JJ, Buu A, Trucco EM, Li C. Alcohol and cannabis co‐use and longitudinal gray matter volumetric changes in early and late adolescence. Addiction Biology 2022, 27: e13208. PMID: 36001427, PMCID: PMC9413216, DOI: 10.1111/adb.13208.Peer-Reviewed Original ResearchConceptsGray matter volumeLate adolescenceCaudal middle frontal cortexEarly adolescent onsetGray matter volumetric changesMiddle frontal cortexSevere alcohol useBrain developmentCross-sectional findingsSocial cognitionExecutive controlNCANDA studyVolumetric declinesSupramarginal gyrusPotential sex differencesSuperior temporalImpact of alcoholAdolescent onsetSubstance useCortical regionsAlcohol useMatter volumeFrontal cortexResult of alcoholMixed-effects modelingCognitive Challenges Are Better in Distinguishing Binge From Nonbinge Drinkers: An Exploratory Deep‐Learning Study of fMRI Data of Multiple Behavioral Tasks and Resting State
Li G, Zhang Z, Chen Y, Wang W, Bi J, Tang X, Li C. Cognitive Challenges Are Better in Distinguishing Binge From Nonbinge Drinkers: An Exploratory Deep‐Learning Study of fMRI Data of Multiple Behavioral Tasks and Resting State. Journal Of Magnetic Resonance Imaging 2022, 57: 856-868. PMID: 35808911, DOI: 10.1002/jmri.28336.Peer-Reviewed Original ResearchConceptsNonbinge drinkersBinge drinkingResting-state functional magnetic resonance imaging (fMRI) dataSignificant group main effectBehavioral tasksSupplementary motor areaGradient-echo echo-planar sequenceMultiple behavioral tasksGroup main effectNodal metricsRight cuneusEcho-planar sequenceMagnetic resonance imaging dataMotor areaRegion of interestFunctional connectivityBingeDrinkersTechnical efficacyNeural responsesFunctional magnetic resonance imaging (fMRI) dataNumber of ROIsP-valueStage 2Human Connectome ProjectLoss and Frontal Striatal Reactivities Characterize Alcohol Use Severity and Rule-Breaking Behavior in Young Adult Drinkers
Li G, Chen Y, Chaudhary S, Tang X, Li CR. Loss and Frontal Striatal Reactivities Characterize Alcohol Use Severity and Rule-Breaking Behavior in Young Adult Drinkers. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 1007-1016. PMID: 35709958, PMCID: PMC10249655, DOI: 10.1016/j.bpsc.2022.06.001.Peer-Reviewed Original Research
2021
Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data
Li G, Chen Y, Le TM, Zhornitsky S, Wang W, Dhingra I, Zhang S, Tang X, Li CR. Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data. Drug And Alcohol Dependence 2021, 224: 108731. PMID: 33915512, PMCID: PMC8641247, DOI: 10.1016/j.drugalcdep.2021.108731.Peer-Reviewed Original ResearchConceptsNon-binge drinkersRight posterior insulaPeer influenceYoung adult binge drinkingSocial cognition tasksSocial cognitive processingAlcohol useBinge drinkingWhole-brain regressionAdult binge drinkingYoung adultsMedial orbitofrontal cortexHuman Connectome ProjectRPI activityAlcohol use severityHuman Connectome Project dataSocial cognitionCognition tasksCognitive processingNeural correlatesNeural processesPotential sex differencesOrbitofrontal cortexPosterior insulaConnectome Project
2019
Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study
Chye Y, Mackey S, Gutman BA, Ching CRK, Batalla A, Blaine S, Brooks S, Caparelli EC, Cousijn J, Dagher A, Foxe JJ, Goudriaan AE, Hester R, Hutchison K, Jahanshad N, Kaag AM, Korucuoglu O, Li C, London ED, Lorenzetti V, Luijten M, Martin‐Santos R, Meda SA, Momenan R, Morales A, Orr C, Paulus MP, Pearlson G, Reneman L, Schmaal L, Sinha R, Solowij N, Stein DJ, Stein EA, Tang D, Uhlmann A, van Holst R, Veltman DJ, Verdejo‐Garcia A, Wiers RW, Yücel M, Thompson PM, Conrod P, Garavan H. Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study. Addiction Biology 2019, 25: e12830. PMID: 31746534, PMCID: PMC7237314, DOI: 10.1111/adb.12830.Peer-Reviewed Original Research
2007
Imaging stress‐ and cue‐induced drug and alcohol craving: association with relapse and clinical implications
SINHA R, LI C. Imaging stress‐ and cue‐induced drug and alcohol craving: association with relapse and clinical implications. Drug And Alcohol Review 2007, 26: 25-31. PMID: 17364833, DOI: 10.1080/09595230601036960.Peer-Reviewed Original ResearchConceptsRelapse outcomesDrug-related cuesPosterior insula regionsCue-induced cravingDrug cue exposureCue-induced drugBrain imaging studiesDrug cuesNeural correlatesCorticostriatal-limbic circuitryCue exposureInsula regionsBrain correlatesRelapse propensityMedial prefrontalBehavioral treatmentAddictive disordersAlcohol cravingPosterior cingulateNeural activityBrain regionsArousal responseLimbic circuitryNeural circuitsCraving