2024
Relationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia
Wang X, Chen W, Gou M, Li W, Li N, Tong J, Zhou Y, Xie T, Yu T, Feng W, Li Y, Chen S, Tian B, Tan S, Wang Z, Pan S, Luo X, Zhang P, Huang J, Tian L, Li C, Tan Y. Relationship between plasma TNF-α levels and agitation symptoms in first episode patients with schizophrenia. BMC Psychiatry 2024, 24: 480. PMID: 38956509, PMCID: PMC11218378, DOI: 10.1186/s12888-024-05796-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansMalePsychiatric Status Rating ScalesPsychomotor AgitationReceptors, Tumor Necrosis Factor, Type ISchizophreniaTumor Necrosis Factor-alphaYoung AdultConceptsPositive and Negative Syndrome ScalePlasma TNF-a levelsAgitation symptomsPANSS-ECEpisode patientsTNF-a levelsPositive and Negative Syndrome Scale total scorePANSS-EC scoreNegative Syndrome ScaleSymptoms of schizophreniaPathophysiology of schizophreniaEnzyme-linked immunosorbent assayTNF-aR1 levelSyndrome ScalePlasma levels of tumor necrosis factor-alphaLevels of tumor necrosis factor-alphaSchizophreniaTotal scoreTumor necrosis factor-alphaNecrosis factor-alphaPlasma TNF-aHealthy controlsFEPImmune abnormalities
2021
The mediating effect of brain-derived neurotrophic factor levels on childhood trauma and psychiatric symptoms in patients with first-episode schizophrenia
Wang L, Yin Y, Zhou Y, Huang J, Zhang P, Chen S, Fan H, Cui Y, Luo X, Tan S, Wang Z, Li CR, Tian B, Tian L, Hong L, Tan Y. The mediating effect of brain-derived neurotrophic factor levels on childhood trauma and psychiatric symptoms in patients with first-episode schizophrenia. Australian & New Zealand Journal Of Psychiatry 2021, 56: 828-835. PMID: 34263656, DOI: 10.1177/00048674211031478.Peer-Reviewed Original ResearchMeSH KeywordsAdverse Childhood ExperiencesBrain-Derived Neurotrophic FactorHumansPsychiatric Status Rating ScalesPsychopathologySchizophreniaConceptsBrain-derived neurotrophic factor levelsSerum brain-derived neurotrophic factor (BDNF) levelsNeurotrophic factor levelsFirst-episode schizophreniaQuestionnaire total scoreNegative Syndrome Scale total scoreChildhood Trauma Questionnaire total scoreScale total scoreNegative Syndrome ScaleFactor levelsTotal scoreChildhood traumaHealthy controlsLower serum brain-derived neurotrophic factor levelsAbnormal brain-derived neurotrophic factorChildhood traumatic experiencesSyndrome ScaleBrain-derived neurotrophic factorPathogenesis of schizophreniaEmotional neglectEnzyme-linked immunosorbentSevere childhood traumaChildhood Trauma QuestionnaireClinical symptomsNeurotrophic factor
2019
Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia
Tong J, Huang J, Luo X, Chen S, Cui Y, An H, Xiu M, Tan S, Wang Z, Yuan Y, Zhang J, Yang F, Li CR, Hong L, Tan Y. Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia. Brain Behavior And Immunity 2019, 81: 213-219. PMID: 31201848, PMCID: PMC6754783, DOI: 10.1016/j.bbi.2019.06.017.Peer-Reviewed Original ResearchConceptsN-methyl-D-aspartate (NMDA) glutamate receptorsFirst-episode patientsNMDAR antibodiesAntibody levelsHealthy controlsSerum anti-NMDAR antibodyTotal scoreAnti-NMDAR antibodiesNMDAR antibody levelsNMDAR-antibody encephalitisElevated levelsReceptor antibody levelsSerum antibody levelsTreatment of schizophreniaPathogenesis of schizophreniaNegative Syndrome ScaleSymptoms of psychosisEnzyme-linked immunosorbentEtiology of schizophreniaMCCB total scoreAntibody encephalitisPatient groupNMDAR dysfunctionSchizophrenia (MATRICS) Consensus Cognitive BatteryGlutamate receptorsDepression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy
Huang Z, Zhao J, Ding K, Lv Y, Zhang C, Chao HH, Li CS, Cheng H. Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy. Medicine 2019, 98: e15301. PMID: 31008981, PMCID: PMC6494378, DOI: 10.1097/md.0000000000015301.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsBreast NeoplasmsCancer SurvivorsCase-Control StudiesDepressionFemaleHumansMemory DisordersMemory, EpisodicMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesSelf ReportConceptsSelf-rating Depression ScaleBreast cancer survivorsBreast cancer patientsCancer survivorsCancer patientsExtensive neuropsychological assessmentSignificant differencesMemory problemsBreast cancerDepression ScaleChemotherapyDepression groupPatientsNeuropsychological assessmentLevel of significanceSurvivorsDepressionScoresSPM scoresMemory QuestionnaireProspective memory problemsGroupPresent resultsCancer
2018
Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement
Yu T, Li Y, Fan F, Cao H, Luo X, Tan S, Yang F, Zhang X, Shugart YY, Hong LE, Li CR, Tan Y. Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement. Scientific Reports 2018, 8: 12884. PMID: 30150749, PMCID: PMC6110787, DOI: 10.1038/s41598-018-31186-y.Peer-Reviewed Original ResearchConceptsGray matter volumeAbnormal Involuntary Movement ScaleTardive dyskinesiaMatter volumeTD severityAntipsychotic medication treatmentCerebral morphological changesAbnormal involuntary movementsBrain structural magnetic resonance imagesPsychopathological symptomsNegative Syndrome ScaleNon-TD groupVoxel-based morphometryMedication treatmentHealthy controlsGMV changesMotor disordersAIMS scoresInvoluntary movementsMovement ScaleStructural magnetic resonance imagesTemporal cortexSchizophrenia patientsLingual gyrusSyndrome Scale
2017
Depression in chronic ketamine users: Sex differences and neural bases
Li CR, Zhang S, Hung CC, Chen CM, Duann JR, Lin CP, Lee TS. Depression in chronic ketamine users: Sex differences and neural bases. Psychiatry Research Neuroimaging 2017, 269: 1-8. PMID: 28892733, PMCID: PMC5634929, DOI: 10.1016/j.pscychresns.2017.09.001.Peer-Reviewed Original ResearchMeSH KeywordsAnesthetics, DissociativeDepressionFemaleGyrus CinguliHumansKetamineMagnetic Resonance ImagingMalePrefrontal CortexPsychiatric Status Rating ScalesSex CharacteristicsSubstance-Related DisordersConceptsHealthy controlsSgACC connectivityChronic ketamine usersKetamine usersOrbitofrontal cortexEpidemiological Studies Depression ScaleSubgenual anterior cingulate cortexSex differencesPathogenesis of depressionCES-D scoresState functional connectivityBilateral superior temporal gyrusChronic ketamine useAnterior cingulate cortexSuperior temporal gyrusNeural basisDepression ScaleDorsomedial prefrontal cortexDepression scoresDepression severityKetamine useCingulate cortexTemporal gyrusFunctional connectivityPrefrontal cortexSex differences in the interacting roles of impulsivity and positive alcohol expectancy in problem drinking: A structural brain imaging study
Ide JS, Zhornitsky S, Hu S, Zhang S, Krystal JH, Li CR. Sex differences in the interacting roles of impulsivity and positive alcohol expectancy in problem drinking: A structural brain imaging study. NeuroImage Clinical 2017, 14: 750-759. PMID: 28413777, PMCID: PMC5385596, DOI: 10.1016/j.nicl.2017.03.015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismBrainBrain MappingFemaleHumansImpulsive BehaviorLinear ModelsMagnetic Resonance ImagingMalePsychiatric Status Rating ScalesSex CharacteristicsSurveys and QuestionnairesYoung AdultConceptsPositive alcohol expectanciesGray matter volumeAlcohol expectanciesAlcohol Use Disorders Identification TestSocial drinkersNon-dependent social drinkersProblem drinkingRole of impulsivityBrain imaging studiesRight posterior insulaSex differencesStructural brain imagingStructural brain imaging studiesNeural basisDisorders Identification TestBarratt impulsivityPsychological factorsImpulsivityMediation analysisPosterior insulaDependent individualsRisk factorsAlcohol misuseLinear modelingGeneral linear modeling
2013
Psychometric properties of the World Health Organization quality of life assessment – brief in methadone patients: a validation study in northern Taiwan
Fu TS, Tuan YC, Yen MY, Wu WH, Huang CW, Chen WT, Li CS, Lee TS. Psychometric properties of the World Health Organization quality of life assessment – brief in methadone patients: a validation study in northern Taiwan. Harm Reduction Journal 2013, 10: 37. PMID: 24325611, PMCID: PMC4029077, DOI: 10.1186/1477-7517-10-37.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHeroin DependenceHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentPsychiatric Status Rating ScalesPsychometricsQuality of LifeSubstance Abuse, IntravenousTaiwanConceptsInjection drug usersWorld Health Organization QualityHealth Organization QualityDrug usersWHOQOL-BREFOrganization QualityFuture treatment outcome studiesMethadone maintenance treatmentBackgroundQuality of lifeImportant outcome measureTreatment outcome studiesInternal consistencyItem-domain correlationsCriterion-related validityPsychometric propertiesMaintenance treatmentMethadone patientsTest-retest reliabilityGeneral healthOverall QoLOutcome measuresOutcome studiesItem response distributionsQOL characteristicsDomain scores
2010
Increased error-related thalamic activity during early compared to late cocaine abstinence
Li CS, Luo X, Sinha R, Rounsaville BJ, Carroll KM, Malison RT, Ding YS, Zhang S, Ide JS. Increased error-related thalamic activity during early compared to late cocaine abstinence. Drug And Alcohol Dependence 2010, 109: 181-189. PMID: 20163923, PMCID: PMC2875333, DOI: 10.1016/j.drugalcdep.2010.01.008.Peer-Reviewed Original Research
2003
Auditory discrimination in female adolescents varying in schizotypal features: Preliminary findings
Li C, Yang Y, Chen M, Chen WJ, Liu J. Auditory discrimination in female adolescents varying in schizotypal features: Preliminary findings. Psychiatry And Clinical Neurosciences 2003, 57: 391-397. PMID: 12839520, DOI: 10.1046/j.1440-1819.2003.01137.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAuditory PerceptionDiscrimination, PsychologicalFemaleHumansNeuropsychological TestsPsychiatric Status Rating ScalesSchizotypal Personality DisorderSurveys and QuestionnairesConceptsSchizotypal Personality QuestionnaireAuditory discriminationPerceptual Aberration ScaleResponse biasSchizotypal featuresSPQ scoresChinese Health QuestionnaireImpaired auditory processingHigher SPQ scoresSignal detection theoryFemale adolescent subjectsPreliminary findingsAuditory perceptionDiscrimination taskAuditory processingImpaired performanceAuditory detectionDetection theoryPersonality QuestionnaireFemale adolescentsAuditory hallucinationsPsychological statusSchizophrenia patientsYoung adultsGroups of subjects