2022
Effects of androgen deprivation on white matter integrity and processing speed in prostate cancer patients.
Chaudhary S, Roy A, Summers C, Ahles T, Li C, Chao H. Effects of androgen deprivation on white matter integrity and processing speed in prostate cancer patients. American Journal Of Cancer Research 2022, 12: 4802-4814. PMID: 36381311, PMCID: PMC9641391.Peer-Reviewed Original ResearchAndrogen deprivation therapyProstate cancer patientsWhite matter integrityCancer patientsAndrogen deprivationFractional anisotropyNon-metastatic prostate cancerSignificant FA changesImpaired white matter integrityPosterior corona radiataAnterior thalamic radiationDiffusion tensor imagingADT patientsDeprivation therapyProspective studyCorpus callosumProstate cancerCorona radiataYears of educationThalamic radiationPatientsWhole brainCognitive deficitsCognitive functionTensor imagingHistory of suicide attempts associated with the thinning right superior temporal gyrus among individuals with schizophrenia
Yin Y, Tong J, Huang J, Tian B, Chen S, Tan S, Wang Z, Yang F, Tong Y, Fan F, Kochunov P, Jahanshad N, Li CR, Hong LE, Tan Y. History of suicide attempts associated with the thinning right superior temporal gyrus among individuals with schizophrenia. Brain Imaging And Behavior 2022, 16: 1893-1901. PMID: 35545740, PMCID: PMC10025969, DOI: 10.1007/s11682-021-00624-3.Peer-Reviewed Original ResearchConceptsRight superior temporal gyrusSuperior temporal gyrusCortical surface areaSuicide attemptsTemporal gyrusSuicide attemptersMean cortical thicknessIndividual brain regionsCortical thinningCortical abnormalitiesHealthy volunteersCortical thicknessGeneral populationThinner cortexMorphometric alterationsWhole brainBrain regionsStructural MRISuicidal behaviorGyrusSchizophreniaHigh rateAttemptersIndividualsGroup
2021
Reward-Related Responses and Tonic Craving in Cocaine Addiction: An Imaging Study of the Monetary Incentive Delay Task
Zhornitsky S, Dhingra I, Le TM, Wang W, Li CR, Zhang S. Reward-Related Responses and Tonic Craving in Cocaine Addiction: An Imaging Study of the Monetary Incentive Delay Task. The International Journal Of Neuropsychopharmacology 2021, 24: 634-644. PMID: 33822080, PMCID: PMC8378081, DOI: 10.1093/ijnp/pyab016.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsCocaine Craving QuestionnaireCCQ scoresRecent cocaine useHealthy controlsMonetary incentive delay taskReward-related responsesCocaine useVentral striatumIncentive delay taskMotor cortexReward responsesPrecentral gyrusCocaine addictionPrimary motor cortexSupplementary motor areaDelay taskIntense drug cravingFunctional magnetic resonance imagingMagnetic resonance imagingDrug-seeking behaviorHigher activationReward-related activityMotor areaWhole brain
2020
A whole‐brain modeling approach to identify individual and group variations in functional connectivity
Zhao Y, Caffo BS, Wang B, Li C, Luo X. A whole‐brain modeling approach to identify individual and group variations in functional connectivity. Brain And Behavior 2020, 11: e01942. PMID: 33210469, PMCID: PMC7821576, DOI: 10.1002/brb3.1942.Peer-Reviewed Original ResearchConceptsWhole-brain functional connectivityFunctional connectivityResting-state functional connectivityVoxel-wise levelMedium-sized cohortBrain areasWhole brainGroup differencesResting-state fMRI datasetsHuman Connectome ProjectMatrix regression methodBrain subnetworksCovariatesConnectome ProjectSubjectsDimension reduction approachStatistical powerCohortModeling approachBrainStatistical methods
2019
Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis
Jenks SK, Zhang S, Li CR, Hu S. Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis. Journal Of Psychiatric Research 2019, 122: 54-63. PMID: 31927266, PMCID: PMC7010552, DOI: 10.1016/j.jpsychires.2019.12.017.Peer-Reviewed Original ResearchConceptsHealthy controlsState functional connectivityStria terminalisFunctional connectivityAnxiety disordersBed nucleus stria terminalisNucleus stria terminalisAnxiety-related disordersBed nucleusClinical heterogeneityComorbid anxietyWhole brainAmygdalaIntrinsic connectivityRSFCNathan Kline Institute-Rockland SampleAnticipatory anxietyBNSTGroup differencesNeural markersDisordersPatientsTerminalisImaging resultsCurrent findings
2018
Diminished gray matter density mediates chemotherapy dosage-related cognitive impairment in breast cancer patients
Li X, Chen H, Lv Y, Chao HH, Gong L, Li CR, Cheng H. Diminished gray matter density mediates chemotherapy dosage-related cognitive impairment in breast cancer patients. Scientific Reports 2018, 8: 13801. PMID: 30218006, PMCID: PMC6138678, DOI: 10.1038/s41598-018-32257-w.Peer-Reviewed Original ResearchConceptsBreast cancer patientsGray matter densityRight middle frontal gyrusBC patientsCancer patientsCognitive impairmentMiddle frontal gyrusChemotherapy cyclesFrontal gyrusWhole brainGray matterMorphometry analysisHealthy control subjectsStructural magnetic resonance imagingDose-response relationshipMagnetic resonance imagingRight fusiform areaFrontal cortical structuresControl subjectsBilateral cerebellumInferior frontal gyrusPatientsLeft inferior frontal gyrusResonance imagingBrain structures
2013
Global Resting-State Functional Magnetic Resonance Imaging Analysis Identifies Frontal Cortex, Striatal, and Cerebellar Dysconnectivity in Obsessive-Compulsive Disorder
Anticevic A, Hu S, Zhang S, Savic A, Billingslea E, Wasylink S, Repovs G, Cole MW, Bednarski S, Krystal JH, Bloch MH, Li CS, Pittenger C. Global Resting-State Functional Magnetic Resonance Imaging Analysis Identifies Frontal Cortex, Striatal, and Cerebellar Dysconnectivity in Obsessive-Compulsive Disorder. Biological Psychiatry 2013, 75: 595-605. PMID: 24314349, PMCID: PMC3969771, DOI: 10.1016/j.biopsych.2013.10.021.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPrefrontal cortexResting-state functional connectivity dataStriatum/nucleus accumbensVentral striatum/nucleus accumbensResting-state functional connectivity studiesVentral anterior cingulate cortexCortico-striatal circuitsMagnetic Resonance Imaging AnalysisAnterior cingulate cortexFunctional connectivity studiesBasal gangliaControl subjectsFunctional connectivity dataAnterior thalamusRight putamenFrontal cortexNucleus accumbensDorsal striatumCerebellar cortexAbnormal neural connectivityCerebellar dysconnectivityCingulate cortexWhole brainFunctional magnetic resonance imaging (fMRI) analysis