2023
Immune-Inflammatory Response And Compensatory Immune-Regulatory Reflex Systems And White Matter Integrity in Schizophrenia
Gou M, Chen W, Li Y, Chen S, Feng W, Pan S, Luo X, Tan S, Tian B, Li W, Tong J, Zhou Y, Li H, Yu T, Wang Z, Zhang P, Huang J, Kochunov P, Tian L, Li C, Hong L, Tan Y. Immune-Inflammatory Response And Compensatory Immune-Regulatory Reflex Systems And White Matter Integrity in Schizophrenia. Schizophrenia Bulletin 2023, 50: 199-209. PMID: 37540273, PMCID: PMC10754202, DOI: 10.1093/schbul/sbad114.Peer-Reviewed Original ResearchConceptsImmune-inflammatory response systemWhite matter integrityNegative symptom scoresFractional anisotropySymptom scoresAffected white matter tractsImmune inflammatory responsePanel of cytokinesWhite matter impairmentEnzyme-linked immunosorbentWhite matter tractsAverage fractional anisotropyWhite matter componentsPeripheral inflammationNeuroinflammatory conditionsPathophysiological mechanismsHealthy controlsCorpus callosumNegative symptomsReflex systemSchizophreniaOligodendrocyte differentiationConsistent findingComposite scoreUnderlying mechanism
2022
Effects of androgen deprivation on white matter integrity and processing speed in prostate cancer patients.
Chaudhary S, Roy A, Summers C, Ahles T, Li C, Chao H. Effects of androgen deprivation on white matter integrity and processing speed in prostate cancer patients. American Journal Of Cancer Research 2022, 12: 4802-4814. PMID: 36381311, PMCID: PMC9641391.Peer-Reviewed Original ResearchAndrogen deprivation therapyProstate cancer patientsWhite matter integrityCancer patientsAndrogen deprivationFractional anisotropyNon-metastatic prostate cancerSignificant FA changesImpaired white matter integrityPosterior corona radiataAnterior thalamic radiationDiffusion tensor imagingADT patientsDeprivation therapyProspective studyCorpus callosumProstate cancerCorona radiataYears of educationThalamic radiationPatientsWhole brainCognitive deficitsCognitive functionTensor imaging
2021
Gender-related neuroanatomical differences in alcohol dependence: findings from the ENIGMA Addiction Working Group
Rossetti MG, Patalay P, Mackey S, Allen NB, Batalla A, Bellani M, Chye Y, Cousijn J, Goudriaan AE, Hester R, Hutchison K, Li CR, Martin-Santos R, Momenan R, Sinha R, Schmaal L, Sjoerds Z, Solowij N, Suo C, van Holst RJ, Veltman DJ, Yücel M, Thompson PM, Conrod P, Garavan H, Brambilla P, Lorenzetti V. Gender-related neuroanatomical differences in alcohol dependence: findings from the ENIGMA Addiction Working Group. NeuroImage Clinical 2021, 30: 102636. PMID: 33857771, PMCID: PMC8065340, DOI: 10.1016/j.nicl.2021.102636.Peer-Reviewed Original ResearchConceptsENIGMA Addiction Working GroupAlcohol dependenceNeuroanatomical differencesAlcohol-dependent menSmaller amygdala volumesGlobal brain measuresGender-related differencesClinical outcomesControl menCorpus callosumAmygdala volumeNeurobiological effectsGM volumeGender differencesSmaller amygdalaStandard drinksBrain regionsIntracranial volumeWorking GroupTotal GMBrain measuresCerebellar GMNeurobiological substratesWomenEducation years