Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene
Zogg CK. Phosphoglycerate Dehydrogenase: Potential Therapeutic Target and Putative Metabolic Oncogene. Journal Of Oncology 2014, 2014: 524101. PMID: 25574168, PMCID: PMC4276281, DOI: 10.1155/2014/524101.Peer-Reviewed Original ResearchRole of PHGDHPotential therapeutic targetMetabolic oncogeneTherapeutic targetEnzyme phosphoglycerate dehydrogenaseTumor suppressors/oncogenesClassic animal studiesPhosphoglycerate dehydrogenaseAnimal studiesWarburg effectMetabolic pathwaysRate-limiting stepOncogenePHGDHMetabolic explanationCancerCell preference