The role of neurotrophins in major depressive disorder
Jiang C, Salton S. The role of neurotrophins in major depressive disorder. Translational Neuroscience 2013, 4: 46-58. PMID: 23691270, PMCID: PMC3656715, DOI: 10.2478/s13380-013-0103-8.Peer-Reviewed Original ResearchBrain-derived neurotrophic factorDepressive behaviorRole of neurotrophinsMajor depressive disorderTransgenic mouse modelStability of synapsesComplex brain circuitryAntidepressant effectsDendritic lengthSpine densityNeurotrophic factorDepressive disorderNeuronal cytoarchitectureNucleus accumbensMouse modelAnalyses of knockoutBrain circuitryPrefrontal cortexNeurotrophinsGrowth factorSingle nucleotide polymorphismsCritical modulatorHuman genetic studiesSubtle alterationsNucleotide polymorphisms