2017
Distribution of Lewis and Secretor polymorphisms and corresponding CA19‐9 antigen expression in a Chinese population
Guo M, Luo G, Lu R, Shi W, Cheng H, Lu Y, Jin K, Yang C, Wang Z, Long J, Xu J, Ni Q, Liu C, Yu X. Distribution of Lewis and Secretor polymorphisms and corresponding CA19‐9 antigen expression in a Chinese population. FEBS Open Bio 2017, 7: 1660-1671. PMID: 29123975, PMCID: PMC5666394, DOI: 10.1002/2211-5463.12278.Peer-Reviewed Original Research
2015
Mature T cell responses are controlled by microRNA-142
Sun Y, Oravecz-Wilson K, Mathewson N, Wang Y, McEachin R, Liu C, Toubai T, Wu J, Rossi C, Braun T, Saunders T, Reddy P. Mature T cell responses are controlled by microRNA-142. Journal Of Clinical Investigation 2015, 125: 2825-2840. PMID: 26098216, PMCID: PMC4563679, DOI: 10.1172/jci78753.Peer-Reviewed Original ResearchConceptsCell cyclingE2F transcription factorsAtypical E2F transcription factorMature T cell responsesCell proliferationShort palindromic repeatsUpregulation of genesMiR-142T cell developmentTranscription factorsBioinformatics analysisTarget genesPalindromic repeatsMolecular approachesMolecular mechanismsCell developmentMolecular processesMicroRNA-142Targeted deletionWT T cellsGenesE2F8E2F7Multiple murine modelsT cell proliferation
2011
Epigenetic regulation of homeobox genes in liver cancer
Liu H, Robertson K, Liu C. Epigenetic regulation of homeobox genes in liver cancer. The FASEB Journal 2011, 25: 794.12-794.12. DOI: 10.1096/fasebj.25.1_supplement.794.12.Peer-Reviewed Original ResearchHox genesEpigenetic regulationHomeobox genesAmino acid DNA-binding domainHox gene regulationDNA-binding domainHox gene familyHCC cell linesBp DNA sequenceCell linesGene familyGene regulationEpigenetic modificationsEpigenetic mechanismsIdentity of cellsTranscription factorsDNA sequencesTrichostatin A.Expression profilesCancer tissuesDifferential expressionGenesCell line experimentsNormal developmentHCC cancer tissuesIdentification of the IFITM3 gene as an inhibitor of hepatitis C viral translation in a stable STAT1 cell line
Yao L, Dong H, Zhu H, Nelson D, Liu C, Lambiase L, Li X. Identification of the IFITM3 gene as an inhibitor of hepatitis C viral translation in a stable STAT1 cell line. Journal Of Viral Hepatitis 2011, 18: e523-e529. PMID: 21914072, PMCID: PMC3736357, DOI: 10.1111/j.1365-2893.2011.01452.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarrier ProteinsCell LineGene ExpressionHepacivirusHumansMembrane ProteinsMiceProtein BiosynthesisProtein MultimerizationReal-Time Polymerase Chain ReactionReceptors, EstrogenRecombinant Fusion ProteinsRNA, ViralRNA-Binding ProteinsSTAT1 Transcription FactorTamoxifenTranscriptional ActivationViral ProteinsConceptsFusion proteinCell linesRNA replicationInterferon-induced transmembrane protein 3Internal ribosomal entry siteHCV IRESHCV internal ribosomal entry siteTransmembrane protein 3HCV RNA replicationMouse estrogen receptorSignal transducerTranscription 1Gene expressionViral translationIFITM3 geneHuh7.5 cell lineReal-time PCRAnti-HCV effectGenesEntry siteElevated expressionProtein 3Western blottingIRESProtein
2009
DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer
Jin B, Yao B, Li J, Fields C, Delmas A, Liu C, Robertson K. DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer. Cancer Research 2009, 69: 7412-7421. PMID: 19723660, PMCID: PMC2745494, DOI: 10.1158/0008-5472.can-09-0116.Peer-Reviewed Original ResearchConceptsDNA methyltransferasesMethylation patternsPolycomb group targetsPRC1/PRC2DNA methylation patternsBisulfite genomic sequencingPRC1 functionRepression complexHistone codeHistone modificationsChromatin immunoprecipitationEpigenetic silencingPanel of genesEpigenetic modifiersReverse transcription-PCRPRC2DNMT3BNovel linkGenomic sequencingGenesDNMT1Colorectal cancer cell linesCell growthCancer cell linesPRC1
2007
No association evidence between schizophrenia and dystrobrevin-binding protein 1 (DTNBP1) in Taiwanese families
Liu C, Liu Y, Fann C, Yang W, Wu J, Hung S, Chen W, Chueh C, Liu W, Liu C, Hsieh M, Hwang T, Faraone S, Tsuang M, Hwu H. No association evidence between schizophrenia and dystrobrevin-binding protein 1 (DTNBP1) in Taiwanese families. Schizophrenia Research 2007, 93: 391-398. PMID: 17407805, DOI: 10.1016/j.schres.2007.02.003.Peer-Reviewed Original ResearchConceptsDystrobrevin-binding protein 1Single locusIntermarker linkage disequilibriumAssociation evidencePositional candidate genesHaplotype association analysisProtein 1Linkage disequilibriumCandidate genesLinkage studiesAssociation analysisHaplotype analysisFamily sampleGenesNo significant associationAffected siblingsEtiology of schizophreniaHaplotypesLociSiblings of schizophreniaTaiwanese familiesSignificant associationTransmit programsSchizophreniaAssociation