2024
The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study
Vranic J, Dmytriw A, Berglar I, Alotaibi N, Cancelliere N, Stapleton C, Rabinov J, Harker P, Gupta R, Bernstock J, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Salem M, Baig A, Namaani K, Kühn A, Pukenas B, Jankowitz B, Burkhardt J, Siddiqui A, Jabbour P, Singh J, Puri A, Regenhardt R, Pereira V, Patel A. The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study. Neurosurgery 2024, 95: 179-185. PMID: 38634693, DOI: 10.1227/neu.0000000000002956.Peer-Reviewed Original ResearchPlatelet function testsPipeline Embolization DeviceDual antiplatelet therapyGroup patientsIntracranial complicationsDAPT regimenThromboembolic complicationsPED treatment of intracranial aneurysmsResults of platelet function testingPipeline Embolization Device embolizationPipeline Embolization Device treatmentFunction testsIntracranial aneurysmsPipeline flow diversionPermanent neurological disabilityInternational multicenter studyFlow diversionTreatment of intracranial aneurysmsUnruptured intracranial aneurysmsWilcoxon rank-sumClopidogrel nonrespondersComplication rateMulticenter studyAntiplatelet therapyFisher's exact
2023
The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study
Vranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.Peer-Reviewed Original ResearchConceptsDual antiplatelet therapyAneurysm occlusion rateAneurysm occlusionDAPT durationThromboembolic complicationsOcclusion rateFlow diversionDuration of DAPTDual antiplatelet therapy durationIntracranial aneurysmsSingle Pipeline Embolization DeviceAntiplatelet therapy durationEndoluminal flow diversionRate of complicationsPrimary outcome measurePipeline Embolization DeviceSignificant differencesUnruptured intracranial aneurysmsAspirin monotherapyAntiplatelet therapyIschemic strokeTherapy durationIatrogenic complicationsRetrospective reviewMulticenter study482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier?
Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Romero C, Stone J, Ebersole K, Fry L, Natarajan S, Thomson B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier? Neurosurgery 2023, 69: 103-104. DOI: 10.1227/neu.0000000000002375_482.Peer-Reviewed Original ResearchTriple therapy groupDual antiplatelet therapyVertebrobasilar fusiform aneurysmsBrainstem compressionIschemic strokeAneurysm characteristicsFusiform aneurysmsFlow diversionIschemic stroke ratePoor natural historyRetrospective data collectionOverall rateAntiplatelet therapyBaseline disabilityHemorrhagic complicationsRadial access useTriple therapyAngiographic outcomesClinical outcomesClinical presentationHigh morbimortalityAdjunctive coilingSimilar patientsMedian numberPerforator occlusion
2022
P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier?
Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Ebersole K, Fry L, Natarajan S, Owusu-Adjei B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier? 2022, a59.1-a59. DOI: 10.1136/neurintsurg-2022-snis.89.Peer-Reviewed Original Research