2016
Pneumococcal Vaccination Strategies. An Update and Perspective
Berical AC, Harris D, Dela Cruz CS, Possick JD. Pneumococcal Vaccination Strategies. An Update and Perspective. Annals Of The American Thoracic Society 2016, 13: 933-944. PMID: 27088424, PMCID: PMC5461988, DOI: 10.1513/annalsats.201511-778fr.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInvasive pneumococcal diseasePneumococcal diseasePneumococcal vaccineNext-generation pneumococcal vaccinesPneumococcal vaccine recommendationsVaccination of infantsPneumococcal polysaccharide vaccineNasal carriage ratePneumococcal conjugate vaccineChronic pulmonary diseaseProtein-conjugate vaccineImplementation of vaccinesMucosal immunity responseBasis of agePneumococcal vaccinationImportant global pathogenPneumococcal pneumoniaPneumococcal infectionPolysaccharide vaccineVaccine recommendationsCommon presentationConjugate vaccinePulmonary diseaseVaccine indicationsCarriage rate
2012
Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses
Dela Cruz CS, Liu W, He CH, Jacoby A, Gornitzky A, Ma B, Flavell R, Lee CG, Elias JA. Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses. Cell Host & Microbe 2012, 12: 34-46. PMID: 22817986, PMCID: PMC3613130, DOI: 10.1016/j.chom.2012.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsCarrier ProteinsCaspase 1Cell DeathChitinase-3-Like Protein 1CytokinesGlycoproteinsHost-Pathogen InteractionsInflammasomesLungMacrophagesMiceMice, Mutant StrainsNLR Family, Pyrin Domain-Containing 3 ProteinPhagocytosisPneumococcal InfectionsPneumonia, PneumococcalReceptors, Purinergic P2X7Streptococcus pneumoniaeConceptsHost toleranceAntibacterial responseChitinase-like proteinsEvolutionary timeHost antibacterial responsesATP accumulationChitinase 3Bacterial clearanceCentral roleMacrophage pyroptosisToleranceBacterial disseminationInflammasome activationStreptococcus pneumoniaeBacterial killingType 17 cytokinesThymic stromal lymphopoietinCHI3L1SpeciesProteinBacteriaLung injuryHostRolePyroptosis