2024
Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine
Petrakis I, Meshberg‐Cohen S, Nich C, Kelly M, Claudio T, Jane J, Pisani E, Ralevski E. Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine. American Journal On Addictions 2024, 33: 525-533. PMID: 38624259, DOI: 10.1111/ajad.13557.Peer-Reviewed Original ResearchCognitive processing therapyIndividual drug counselingPosttraumatic stress disorderOpioid use disorderSubstance use disordersDrug counselingProcessing therapyPTSD symptomsUse disorderCognitive processing therapy groupEvidence-based trauma-focused psychotherapiesSelf-reported PTSD symptomsPosttraumatic stress disorder symptomsPosttraumatic stress disorder treatmentRemission of PTSD symptomsPosttraumatic Stress Disorder ChecklistComorbid opioid use disorderTrauma-focused psychotherapyTrauma-focused treatmentRates of comorbidityTreatment group differencesPCL-5Stress disorderGroup differencesRandomized clinical trials
2019
Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder
DeVito EE, Carroll KM, Babuscio T, Nich C, Sofuoglu M. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal Of Substance Use And Addiction Treatment 2019, 107: 29-37. PMID: 31757262, PMCID: PMC6918721, DOI: 10.1016/j.jsat.2019.08.009.Peer-Reviewed Original ResearchConceptsCocaine use disorderSignificant treatment group differencesUse disordersEfficacy of galantamineTreatment-seeking cocaine usersCurrent cocaine use disordersGroup differencesCocaine use outcomesSample of individualsTreatment group differencesComorbid opioid use disorderMethadone-maintained individualsMemory capacityAbstinent individualsCocaine useCognitive improvementCognitive outcomesCocaine use reductionCognitive functionUse outcomesCocaine usersGalantamine groupIndividualsDisordersInitial promise
2016
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM. Carvedilol does not reduce cocaine use in methadone-maintained cocaine users. Journal Of Substance Use And Addiction Treatment 2016, 73: 63-69. PMID: 28017186, PMCID: PMC5193370, DOI: 10.1016/j.jsat.2016.11.005.Peer-Reviewed Original ResearchConceptsEfficacy of carvedilolCocaine-positive urinesSignificant group differencesCocaine use disorderCocaine useOpioid usePositive urineGroup differencesOpioid-positive urinesCAR groupMain outcome measuresUrine drug screeningOpioid-dependent participantsSelf-reported drug useSelf-reported daysOverall treatment effectCocaine-dependent participantsTreatment armsAdrenergic blockersTreatment responseOutcome measuresPlaceboWithdrawal severityStudy participationTreatment retention
2014
Progesterone for the reduction of cocaine use in post-partum women with a cocaine use disorder: a randomised, double-blind, placebo-controlled, pilot study
Yonkers KA, Forray A, Nich C, Carroll KM, Hine C, Merry BC, Shaw H, Shaw J, Sofuoglu M. Progesterone for the reduction of cocaine use in post-partum women with a cocaine use disorder: a randomised, double-blind, placebo-controlled, pilot study. The Lancet Psychiatry 2014, 1: 360-367. PMID: 25328863, PMCID: PMC4199242, DOI: 10.1016/s2215-0366(14)70333-5.Peer-Reviewed Original ResearchCocaine use disorderCocaine usePostpartum womenPost trialUse disordersPlacebo-controlled pilot trialOral micronized progesteronePositive urine testPost-partum womenGroup differencesSelf-reported daysMultiple brain functionsUse of cocaineMicronized progesteroneObstetrical clinicTherapeutic breakProgesterone replacementAdverse eventsUS National InstitutesProgesterone treatmentUrine testsPilot trialRate of submissionStudy biostatisticianProgesterone
2010
Coping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders
Sugarman DE, Nich C, Carroll KM. Coping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders. Psychology Of Addictive Behaviors 2010, 24: 689-695. PMID: 21198228, PMCID: PMC3059590, DOI: 10.1037/a0021584.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyStrategy useObserver ratingsComputerized cognitive behavioral therapyCoping Strategy UseOutpatient substance abuse treatment facilitiesSubstance abuse treatment facilitiesCoping Strategies ScaleRole-play assessmentComputer-based versionSignificant group differencesSubstance use disordersCoping strategiesStrategies ScaleGroup differencesSubstance usersSubstance dependenceUse disordersCBT4CBTDifferential effectsSkillsDrug useDrug-related outcomesParticipantsRatings