2019
Subgenomic flavivirus RNA binds the mosquito DEAD/H-box helicase ME31B and determines Zika virus transmission by Aedes aegypti
Göertz GP, van Bree JWM, Hiralal A, Fernhout BM, Steffens C, Boeren S, Visser TM, Vogels CBF, Abbo SR, Fros JJ, Koenraadt CJM, van Oers MM, Pijlman GP. Subgenomic flavivirus RNA binds the mosquito DEAD/H-box helicase ME31B and determines Zika virus transmission by Aedes aegypti. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 19136-19144. PMID: 31488709, PMCID: PMC6754610, DOI: 10.1073/pnas.1905617116.Peer-Reviewed Original ResearchConceptsSubgenomic flavivirus RNAInfectious blood mealZika virusMosquito infectionWild-type Zika virusesFlavivirus RNAMosquito midgut barrierArthropod-borne flavivirusZika virus transmissionBlood mealGlobal human health threatMosquito cell culturesZIKV infectionMosquito salivaIntrathoracic injectionViral Small Interfering RNAsInfected mosquitoesViral titersAntiviral activityFlavivirus replicationFlavivirus transmissionMidgut barrierHealth threatInfectionInfected cells
2017
Vector competence of European mosquitoes for West Nile virus
Vogels CB, Göertz GP, Pijlman GP, Koenraadt CJ. Vector competence of European mosquitoes for West Nile virus. Emerging Microbes & Infections 2017, 6: 1-13. PMID: 29116220, PMCID: PMC5717085, DOI: 10.1038/emi.2017.82.Peer-Reviewed Original Research