2017
Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma
Hardee S, Prasad ML, Hui P, Dinauer CA, Morotti RA. Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma. Pediatric And Developmental Pathology 2017, 20: 206-212. PMID: 28521635, DOI: 10.1177/1093526616689628.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerPediatric papillary thyroid cancerPrognostic implicationsPediatric papillary thyroid carcinomaNegative casesBRAF-negative casesBRAF-negative patientsBRAF-positive casesTertiary medical centerAggressive clinical coursePapillary thyroid carcinomaSurgical pathology diagnosisCommon genetic aberrationsNegative patientsAggressive courseClinical coursePathologic characteristicsCase seriesClinical outcomesRetrospective reviewAggressive featuresPediatric casesRecurrence rateRetrospective studySingle institution
2000
Over‐expression of hepatocyte growth factor/scatter factor (HGF/SF) and the HGF/SF receptor (cMET) are associated with a high risk of metastasis and recurrence for children and young adults with papillary thyroid carcinoma
Ramirez R, Hsu D, Patel A, Fenton C, Dinauer C, Tuttle R, Francis G. Over‐expression of hepatocyte growth factor/scatter factor (HGF/SF) and the HGF/SF receptor (cMET) are associated with a high risk of metastasis and recurrence for children and young adults with papillary thyroid carcinoma. Clinical Endocrinology 2000, 53: 635-644. PMID: 11106926, DOI: 10.1046/j.1365-2265.2000.01124.x.Peer-Reviewed Original ResearchConceptsPapillary thyroid carcinomaFollicular thyroid carcinomaDisease-free survivalHGF/SF expressionMedullary thyroid carcinomaThyroid carcinomaHepatocyte growth factor/scatter factorGrowth factor/scatter factorYoung adultsFree survivalHigh riskHGF/SF receptorHGF/SFShorter disease-free survivalNormal thyroidExtent of diseaseSF expressionBenign thyroid disordersExpression of cMetIntensity of expressionMalignant thyroid lesionsClinical outcomesRetrospective groupThyroid disordersThyroid cancerThe Expression of Vascular Endothelial Growth Factor and the Type 1 Vascular Endothelial Growth Factor Receptor Correlate with the Size of Papillary Thyroid Carcinoma in Children and Young Adults
Fenton C, Patel A, Dinauer C, Robie D, Tuttle R, Francis G. The Expression of Vascular Endothelial Growth Factor and the Type 1 Vascular Endothelial Growth Factor Receptor Correlate with the Size of Papillary Thyroid Carcinoma in Children and Young Adults. Thyroid 2000, 10: 349-357. PMID: 10807064, DOI: 10.1089/thy.2000.10.349.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinoma, FollicularAdolescentAdultCarcinoma, PapillaryCase-Control StudiesChildEndothelial Growth FactorsFemaleHumansLymphokinesMaleProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Growth FactorThyroid NeoplasmsVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-1Vascular Endothelial Growth FactorsConceptsVascular endothelial growth factorExpression of VEGFPapillary thyroid carcinomaEndothelial growth factorThyroid carcinomaBenign lesionsYoung adultsClinical outcomesThyroid cancerPTC sizeVEGF expressionFlt-1Growth factorRetrospective clinical outcomesChildhood thyroid cancerThyroid tissue blocksFollicular thyroid carcinomaFlt-1 expressionRecurrent diseaseSolid tumorsCarcinomaVEGF receptorsReceptor correlatesLesionsTissue blocks