2022
Low-Intensity Adjuvant Chemotherapy for Breast Cancer in Older Women: Results From the Prospective Multicenter HOPE Trial
Sedrak M, Sun C, Ji J, Cohen H, Gross C, Tew W, Klepin H, Wildes T, Dotan E, Freedman R, O'Connor T, Chow S, Fenton M, Moy B, Chapman A, Dale W, Katheria V, Kuderer N, Lyman G, Magnuson A, Muss H. Low-Intensity Adjuvant Chemotherapy for Breast Cancer in Older Women: Results From the Prospective Multicenter HOPE Trial. Journal Of Clinical Oncology 2022, 41: 316-326. PMID: 36455189, PMCID: PMC9839299, DOI: 10.1200/jco.22.01440.Peer-Reviewed Original ResearchConceptsLow relative dose intensityRelative dose intensityAdjuvant chemotherapyHOPE trialDose intensityOlder patientsOlder womenBreast cancer benefitPrespecified secondary analysisCurative-intent treatmentInferior survival outcomesChemotherapy dose intensityKaplan-Meier methodLow performance statusMultivariable logistic regressionLog-rank testOverall survival probabilityToxic side effectsCancer benefitOverall survivalPerformance statusStandard chemotherapySupportive carePrimary outcomeSurvival outcomes
2019
Impact of an oncology urgent care clinic on emergency department rates.
Sedghi T, Canavan M, Gross C, Davidoff A, Gould Rothberg BE, Strait M, Sinanis N, Adelson K. Impact of an oncology urgent care clinic on emergency department rates. Journal Of Clinical Oncology 2019, 37: 6615-6615. DOI: 10.1200/jco.2019.37.15_suppl.6615.Peer-Reviewed Original ResearchUrgent care clinicED visit ratesSmilow Cancer HospitalVisit ratesProvider visitsED utilizationED visitsCare clinicsUnique patientsEmergency departmentAcute medical attentionUnscheduled emergency departmentRegular clinic visitsCommon cancer typesLower ED utilizationEmergency department ratesFull study sampleTwo-sample t-testClinic visitsSupportive careOncology providersED useSymptom managementCancer HospitalCancer Center