2011
Subclinical vitamin A deficiency does not increase development of tumors in irradiated or unirradiated lungs
Rockwell S, Liu Y, Mayne ST, Redlich CA. Subclinical vitamin A deficiency does not increase development of tumors in irradiated or unirradiated lungs. Experimental Biology And Medicine 2011, 236: 1173-1179. PMID: 21844122, PMCID: PMC3207150, DOI: 10.1258/ebm.2011.011082.Peer-Reviewed Original ResearchConceptsWhole lung irradiationSubclinical vitaminSpontaneous lung metastasesLung metastasesLung tumorsVitamin ALung irradiationTumor cellsLow vitaminDeficient dietSubcutaneous tumorsPossible modifiable risk factorsSeverity of pneumonitisModifiable risk factorsRadiation-induced pneumonitisEnhancement of metastasisImpact of vitaminDose-dependent increaseLevels of retinolGrowth of tumorsDevelopment of tumorsDose-response curveLung injuryLung levelsPrimary cancer
1998
Vitamin A Inhibits Radiation-Induced Pneumonitis in Rats 1 , 2
Redlich C, Rockwell S, Chung J, Sikora A, Kelley M, Mayne S. Vitamin A Inhibits Radiation-Induced Pneumonitis in Rats 1 , 2. Journal Of Nutrition 1998, 128: 1661-1664. PMID: 9772133, DOI: 10.1093/jn/128.10.1661.Peer-Reviewed Original ResearchConceptsRadiation-induced lung injuryVitamin ALung injuryLung inflammationRadiation-induced lung inflammationLung retinol levelsSupplemental vitamin AAltered vitaminThoracic radiationThoracic radiotherapyBronchoalveolar lavagePrescribed dietRetinol levelsDeficient groupDeficient dietTotal doseY ratsRadioprotective agentsRats 1RatsWhole thoraxHost susceptibilityDietInflammationInjury
1990
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction.
Omiecinski C, Redlich C, Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. Cancer Research 1990, 50: 4315-21. PMID: 1694720.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsBase SequenceBlotting, NorthernBlotting, SouthernCytochrome P-450 Enzyme SystemDNAGene Expression Regulation, EnzymologicGenesIsoenzymesLiverMethylcholanthreneMolecular Sequence DataOligonucleotide ProbesOrgan SpecificityPhenobarbitalPolymerase Chain ReactionRatsRats, Inbred StrainsReference ValuesRNARNA, MessengerConceptsPolymerase chain reactionHuman pulmonary alveolar macrophagesChain reactionP450IA1 mRNAEarly gestational stageEnvironmental chemical exposuresPulmonary alveolar macrophagesDevelopmental ageTransplacental treatmentFetal ratsHuman gestationGestational stagesRat lungAlveolar macrophagesDay 15Related cancersHuman tissue samplesIndividual susceptibilityDay 45Fetal liver developmentTarget cellsMRNA expression patternsRatsTissue samplesChemical exposure