Drug-Responsive Symptoms in Melancholia
Nelson J, Mazure C, Quinlan D, Jatlow P. Drug-Responsive Symptoms in Melancholia. JAMA Psychiatry 1984, 41: 663-668. PMID: 6732425, DOI: 10.1001/archpsyc.1984.01790180033004.Peer-Reviewed Original ResearchConceptsPlasma desipramine concentrationsTricyclic antidepressant treatmentHamilton Depression ScalePretreatment symptom severityAntidepressant treatmentDesipramine treatmentDesipramine concentrationsDepression ScaleDepressive symptomsSymptomsSymptom severityDesipramine hydrochlorideDrug responseMultiple regression analysisPatientsRegression analysisTreatmentMelancholia