2021
Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis
Zeiss CJ, Compton S, Veenhuis RT. Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis. ILAR Journal 2021, 62: ilab007-. PMID: 33836527, PMCID: PMC8083356, DOI: 10.1093/ilar/ilab007.Peer-Reviewed Original ResearchConceptsSARS-CoV-2SARS-CoVViral sheddingImmune responseSpontaneous modelAnimal modelsDisease pathogenesisSARS-CoV-2 infectionCOVID-19Severe acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusChimeric SARS-CoVRole of comorbiditiesCoronavirus disease 2019 (COVID-19) pandemicShort-term immune responseWild-type miceSeverity of diseaseOrgan-specific pathologySARS-CoV-2 virusDisease 2019 pandemicAfrican green monkeysTest therapeuticsVaccine approachesNonfatal diseaseTissue involvement
2017
Immune responses to the real world
Zeiss CJ, Brayton CF. Immune responses to the real world. Lab Animal 2017, 47: 13-14. PMID: 29297473, DOI: 10.1038/laban.1384.Peer-Reviewed Original Research
2005
Neuroanatomical Phenotyping in the Mouse: The Dopaminergic System
Zeiss CJ. Neuroanatomical Phenotyping in the Mouse: The Dopaminergic System. Veterinary Pathology 2005, 42: 753-773. PMID: 16301571, DOI: 10.1354/vp.42-6-753.Peer-Reviewed Original ResearchConceptsCentral dopaminergic systemDopaminergic systemBasal nucleusMouse modelHuntington's diseaseTyrosine hydroxylase immunohistochemistryNonhuman primate brainAttention deficit hyperactivity disorderIndividual mouse modelsDeficit hyperactivity disorderSpecific anatomic regionsHydroxylase immunohistochemistryDopaminergic dysfunctionDopamine metabolismHuman neurologic disordersNeurologic disordersPrimate brainReceptor functionPaucity of informationVoluntary movementAnatomic regionsDiseaseMiceHyperactivity disorderMotor testsCNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina
Zeiss CJ, Allore HG, Towle V, Tao W. CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina. Experimental Eye Research 2005, 82: 395-404. PMID: 16143329, DOI: 10.1016/j.exer.2005.07.014.Peer-Reviewed Original ResearchConceptsCiliary neurotrophic factorInner retinal thicknessRetinitis pigmentosaRetinal thicknessGanglion cellsEffects of CNTFInner nuclear layer thicknessNormal retinal electrophysiologyGanglion cell morphologyOuter nuclear layerWild-type retinasDose-dependent mannerDose-dependent alterationsContralateral eyeControl dogsNeurotrophic factorExpression of rhodopsinRetinal electrophysiologyNuclear layerProtective effectRetinal morphologyEntire retinaAnimal modelsCone arrestinCanine model