2022
Brain–phenotype models fail for individuals who defy sample stereotypes
Greene AS, Shen X, Noble S, Horien C, Hahn CA, Arora J, Tokoglu F, Spann MN, Carrión CI, Barron DS, Sanacora G, Srihari VH, Woods SW, Scheinost D, Constable RT. Brain–phenotype models fail for individuals who defy sample stereotypes. Nature 2022, 609: 109-118. PMID: 36002572, PMCID: PMC9433326, DOI: 10.1038/s41586-022-05118-w.Peer-Reviewed Original ResearchConceptsBrain-phenotype relationshipsBrain functional organizationCognitive constructsIndividual differencesNeurocognitive measuresBrain activityNeurocognitive scoresStereotypical profileNeural targetsClinical interventionsNeural circuitsFunctional organizationIndividualsSuch relationshipsData-driven approachRelationshipStereotypes
2020
Education differentially contributes to cognitive reserve across racial/ethnic groups
Avila JF, Rentería MA, Jones RN, Vonk JMJ, Turney I, Sol K, Seblova D, Arias F, Hill‐Jarrett T, Levy S, Meyer O, Racine AM, Tom SE, Melrose RJ, Deters K, Medina LD, Carrión CI, Díaz‐Santos M, Byrd DR, Chesebro A, Colon J, Igwe KC, Maas B, Brickman AM, Schupf N, Mayeux R, Manly JJ. Education differentially contributes to cognitive reserve across racial/ethnic groups. Alzheimer's & Dementia 2020, 17: 70-80. PMID: 32827354, PMCID: PMC8376080, DOI: 10.1002/alz.12176.Peer-Reviewed Original ResearchConceptsWashington Heights-Inwood Columbia Aging ProjectCognitive reserveGrowth curve modelingEducational attainmentStructural magnetic resonance imagingLanguage performanceLanguage trajectoriesLanguage declineCurve modelingAging ProjectHigher educational attainmentMemoryCortical thinningEthnic groupsWMH burdenAttainmentMagnetic resonance imagingNegative impactResonance imagingRace/ethnicity