2021
Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors
Long AS, Zhang AD, Meyer CE, Egilman AC, Ross JS, Wallach JD. Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors. JAMA Network Open 2021, 4: e215731. PMID: 33956134, PMCID: PMC8103227, DOI: 10.1001/jamanetworkopen.2021.5731.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsSafety end pointEnd pointClinical trialsDrug pairsPrimary end point resultsEnd point resultsImproved efficacyEfficacy end pointCochrane Central RegistrySeparate end pointsSingle-enantiomer drugsSingle enantiomer formulationPrimary efficacySecondary efficacyControlled TrialsOvid EmbaseOvid MEDLINESuperior efficacyDrug AdministrationCentral RegistrySystematic reviewMore efficacyTrialsRacemic drugs
2019
Systematic Review of Chronic Discrimination and Changes in Biology During Pregnancy Among African American Women
Chaney C, Lopez M, Wiley KS, Meyer C, Valeggia C. Systematic Review of Chronic Discrimination and Changes in Biology During Pregnancy Among African American Women. Journal Of Racial And Ethnic Health Disparities 2019, 6: 1208-1217. PMID: 31385262, DOI: 10.1007/s40615-019-00622-8.Peer-Reviewed Original ResearchConceptsChronic racial discriminationAfrican American womenSystematic reviewAmerican womenRacial health disparitiesInclusion criteriaMaternal biologyLarger sample sizeCardiovascular systemChronic discriminationHealth disparitiesHealth existLiterature searchPregnancyPsycINFO databasesRelevant biomarkersStudy designSmall sample sizeSample sizeEffective study designPreliminary evidenceCurrent literatureWomenIndirect evidenceInformative method