2024
Pulmonary complications of advanced chronic liver diseases: an updated review
Thevenot T, Raevens S, Aujayeb A, Banini B, Cadranel J, DuBrock H. Pulmonary complications of advanced chronic liver diseases: an updated review. Exploration Of Digestive Diseases 2024, 3: 301-325. DOI: 10.37349/edd.2024.00053.Peer-Reviewed Original ResearchPulmonary complicationsHepatopulmonary syndromeLiver transplantationHepatic hydrothoraxAdvanced chronic liver diseasePre-existing lung diseasePathophysiology of HHLack of routine screeningChronic liver diseaseLiver transplant survivalMultidisciplinary team approachPortopulmonary hypertensionCirrhotic populationCurative therapyPortal hypertensionIncreasing dyspneaTherapeutic optionsClinical featuresMELD exception pointsAwaiting transplantationLung diseasePatient populationLiver diseaseComplicationsTransplant survival
2022
Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4
Banini BA, Patel S, Yu JW, Kang L, Bailey C, Strife BJ, Siddiqui MS, Patel V, Matherly SC, Lee H, Lewis S, Cherian R, Stravitz RT, Luketic V, Sanyal AJ, Sterling RK. Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4. Journal Of Clinical Gastroenterology 2022, 57: 189-197. PMID: 34999644, PMCID: PMC9271129, DOI: 10.1097/mcg.0000000000001664.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientSignificant portal hypertensionFIB-4Chronic liver diseaseAdvanced fibrosisPortal hypertensionLiver biopsyLiver diseasePlatelet countPositive predictive value 27Negative predictive value 99Venous pressure gradientTransjugular liver biopsyGold standardInternal bootstrap validationExternal validationLiver histologyFibrosis indexCurrent gold standardTransient elastographyOptimal cutoffBootstrap validationPatientsSpecificity 67Value 99