2016
Cognitive Priming and Cognitive Training: Immediate and Far Transfer to Academic Skills in Children
Wexler BE, Iseli M, Leon S, Zaggle W, Rush C, Goodman A, Esat Imal A, Bo E. Cognitive Priming and Cognitive Training: Immediate and Far Transfer to Academic Skills in Children. Scientific Reports 2016, 6: 32859. PMID: 27615029, PMCID: PMC5018694, DOI: 10.1038/srep32859.Peer-Reviewed Original ResearchMeSH KeywordsAcademic SuccessChildCognitionFemaleHumansMaleMathematicsMemory, Short-TermPsychomotor PerformanceReadingTransfer, PsychologyVideo GamesConceptsCognitive primingBrain trainingBrain training gamesSecond-grade childrenCognitive trainingCognitive operationsFar transferTraining gamesAcademic skillsAcademic achievementNeural systemsAchievement testTraining sessionsNeuroplastic potentialEnvironmental inputsPrimingTrainingInter-neuronal connectionsChildrenGameStudy sampleSkillsImmediate effectsControl classLearning
2008
Predictors of change in life skills in schizophrenia after cognitive remediation
Kurtz MM, Seltzer JC, Fujimoto M, Shagan DS, Wexler BE. Predictors of change in life skills in schizophrenia after cognitive remediation. Schizophrenia Research 2008, 107: 267-274. PMID: 19006657, PMCID: PMC3399665, DOI: 10.1016/j.schres.2008.10.014.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAttentionCognition DisordersComprehensionComputer-Assisted InstructionFemaleHumansInhibition, PsychologicalMemory, Short-TermMiddle AgedNeuropsychological TestsProblem SolvingPrognosisPsychiatric Status Rating ScalesPsychometricsPsychomotor PerformanceRemedial TeachingSchizophreniaSchizophrenic PsychologySocializationSoftwareVerbal LearningYoung AdultConceptsCognitive remediationAuditory attentionPerformance-based measuresRemediation interventionsComputer-assisted cognitive remediationLife skillsCognitive remediation interventionsSustained auditory attentionEveryday life skillsTreatment-related improvementTreatment process variablesOutpatient rehabilitation treatmentPredictors of changeMeasures of symptomsVerbal abilityVerbal learningTreatment outcome measuresNeurocognitive variablesNeurocognitive functionMemoryNegative symptomsSchizoaffective disorderPredictor studiesCurrent studySchizophrenia
2007
Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance
Bell M, Fiszdon J, Greig T, Wexler B, Bryson G. Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance. The Journal Of Rehabilitation Research And Development 2007, 44: 761. PMID: 17943687, DOI: 10.1682/jrrd.2007.02.0032.Peer-Reviewed Original ResearchConceptsNeurocognitive enhancement therapyWork therapyEnhancement therapyExecutive function tasksComputer-based trainingNonverbal memoryFunction tasksExecutive functionNeuropsychological performanceNeuropsychological testsNeuropsychological assessmentCognitive deficitsCompletion of trainingNeuropsychological improvementOccupational dysfunctionMemorySchizoaffective disorderCurrent studySchizophreniaTrainingJob placementWork activitiesActive interventionTaskAnalysis of variance
2005
Differences in performance and learning proficiency on the Wisconsin Card Sorting Test in schizophrenia: Do they reflect distinct neurocognitive subtypes with distinct functional profiles?
Kurtz MM, Wexler BE. Differences in performance and learning proficiency on the Wisconsin Card Sorting Test in schizophrenia: Do they reflect distinct neurocognitive subtypes with distinct functional profiles? Schizophrenia Research 2005, 81: 167-171. PMID: 16243489, DOI: 10.1016/j.schres.2005.09.003.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAttentionCognition DisordersCuesDiscrimination LearningFemaleHumansLearning DisabilitiesMaleMemory, Short-TermMiddle AgedNeuropsychological TestsPractice, PsychologicalProblem SolvingPsychometricsPsychomotor PerformanceReaction TimeSchizophreniaSchizophrenic PsychologyConceptsWisconsin Card Sorting TestUCSD Performance-based Skills AssessmentCard Sorting TestSorting TestComprehensive neurocognitive test batteryPerformance-Based Skills AssessmentDifferent neurocognitive profilesNeurocognitive test batteryPerformance-based measuresBehavioral treatment interventionsSecond measureNeurocognitive subtypesNeurocognitive profileMotor sequencingWCST performancePoor learnersTest batteryGood learnersDistinct functional profilesSubtyping of patientsTreatment interventionsIndependent measuresLearnersSkills assessmentGreater functional capacity
2001
Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance
Bell M, Bryson G, Greig T, Corcoran C, Wexler BE. Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance. JAMA Psychiatry 2001, 58: 763-768. PMID: 11483142, DOI: 10.1001/archpsyc.58.8.763.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCognitionCognition DisordersComputer-Assisted InstructionDichotic Listening TestsFeedbackFemaleFrontal LobeHumansMaleMemoryMultivariate AnalysisNeuropsychological TestsOccupational TherapyPsychomotor PerformancePsychotic DisordersSchizophreniaSchizophrenic PsychologyTeachingTreatment OutcomeConceptsNeurocognitive enhancement therapyEnhancement therapyWork therapyMental activityNeuropsychological testingLarge effect size improvementsExecutive function tasksNeuropsychological test performanceEffect size improvementsComputer-based trainingFunction tasksExecutive functionMemory performanceCognitive performanceNeuropsychological testsTraining tasksCognitive deficitsTest performanceComputer trainingCognitive dysfunctionIndependent outcome measureOccupational dysfunctionNatural contextSchizoaffective disorderMemory
1995
Comments on “Diminished cerebral metabolic response to motor stimulation in schizophrenics” by Guenther et al. (Eur Arch Psychiatry Clin Neurosci, 1994, 244: 115–125)
Wexler B. Comments on “Diminished cerebral metabolic response to motor stimulation in schizophrenics” by Guenther et al. (Eur Arch Psychiatry Clin Neurosci, 1994, 244: 115–125). European Archives Of Psychiatry And Clinical Neuroscience 1995, 246: 60-60. PMID: 8773220, DOI: 10.1007/bf02191816.Commentaries, Editorials and LettersBehavioral laterality in individuals with Gilles de la Tourette's syndrome and basal ganglia alterations: A preliminary report
Yazgan M, Peterson B, Wexler B, Leckman J. Behavioral laterality in individuals with Gilles de la Tourette's syndrome and basal ganglia alterations: A preliminary report. Biological Psychiatry 1995, 38: 386-390. PMID: 8547458, DOI: 10.1016/0006-3223(94)00302-j.Peer-Reviewed Original ResearchConceptsGTS patientsTourette syndromeIntact basal ganglia functionGilles de la Tourette's syndromeGTS subjectsAdult GTS patientsBasal ganglia alterationsBasal ganglia functionLa Tourette's syndromePrevious MRI studiesNeuropsychological measuresFunctional asymmetryGanglia functionTic symptomsNormal controlsMRI studiesSyndromePreliminary reportPatientsNeuropsychological tasksFunctional significanceSubjectsBehavioral lateralitySymptomsAbnormalities
1994
Abnormalities in rapid, automatic aspects of attention in schizophrenia: blunted inhibition of return
Huey E, Wexler B. Abnormalities in rapid, automatic aspects of attention in schizophrenia: blunted inhibition of return. Schizophrenia Research 1994, 14: 57-63. PMID: 7893622, DOI: 10.1016/0920-9964(94)90009-4.Peer-Reviewed Original ResearchConceptsHealthy subjectsHealthy control subjectsStable schizophrenic outpatientsInhibition of returnMs intervalsControl subjectsSchizophrenic outpatientsNormal intervalsInhibitory mechanismInhibitionVisual stimuliSchizophrenicsSubjectsStimuliIntervalPresent experimentsOutpatientsAbnormalitiesSchizophrenia
1993
Asymmetrical Visual Deprivation: A Technique to Differentially Influence Lateral Hemispheric Function
Levick S, Wexler B, Lorig T, Gur R, Gur R, Schwartz G. Asymmetrical Visual Deprivation: A Technique to Differentially Influence Lateral Hemispheric Function. Perceptual And Motor Skills 1993, 76: 1363-1382. PMID: 8337093, DOI: 10.2466/pms.1993.76.3c.1363.Peer-Reviewed Original ResearchConceptsVisual deprivationHemispheric functionCross-modal influencesSpatial orientation taskPerception of pleasantnessLine bisection testVisual attentionVerbal reasoningContact lens methodIntegrated brainOrientation taskLeft hemisphereMood statesEEG thetaMore thetaLateral asymmetryActivation balanceGeneral hypothesisThetaPleasantnessDeprivationHemisphereInput deprivationPerceptionTask