2024
Do Transtibial Amputations Outperform Amputations of the Hind- and Midfoot Following Severe Limb Trauma?
Fram B, Bosse M, Odum S, Reider L, Gary J, Gordon W, Teague D, Alkhoury D, MacKenzie E, Seymour R, Karunakar M. Do Transtibial Amputations Outperform Amputations of the Hind- and Midfoot Following Severe Limb Trauma? Journal Of Bone And Joint Surgery 2024, 106: 776-781. PMID: 38512987, DOI: 10.2106/jbjs.23.00878.Peer-Reviewed Original ResearchConceptsShort Musculoskeletal Function AssessmentTranstibial amputationDistal amputationMidfoot amputationSevere lower-extremity injuriesLower-extremity injuriesLower-limb injuriesMusculoskeletal Function AssessmentPatient-reported outcomesMonths post-injuryBrief Pain IndexSevere limb traumaDescription of levels of evidenceTranstibial amputeesLevel of evidenceFoot traumaSMFA scoresAmputation revisionTherapeutic Level IIIYears of ageBother indexMidfootAmputation healingAverage SMFA scoreEmotional status
2022
Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings
Goswami K, Tipton C, Clarkson S, Chang G, Tan TL, Fram B, Chisari E, Sobol K, Natoli RM, Conway JD, Altman GT, Parvizi J, Krieg JC. Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings. Journal Of Orthopaedic Trauma 2022, 36: s40-s46. PMID: 35061650, DOI: 10.1097/bot.0000000000002305.Peer-Reviewed Original ResearchConceptsPersistent nonunionLong bone nonunionOpen surgical interventionProspective multicenter studySignificant risk factorsAcute fracturesDevastating complicationIntraoperative specimensMulticenter studySurgical interventionFracture nonunionNonunion diagnosisRisk factorsNGS detectionNonunionUseful adjunctFracture healingClinical specimensPatientsClinical implicationsLevel IIMore casesNGS diagnosticsControl casesBacterial profiles