2022
Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings
Goswami K, Tipton C, Clarkson S, Chang G, Tan TL, Fram B, Chisari E, Sobol K, Natoli RM, Conway JD, Altman GT, Parvizi J, Krieg JC. Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings. Journal Of Orthopaedic Trauma 2022, 36: s40-s46. PMID: 35061650, DOI: 10.1097/bot.0000000000002305.Peer-Reviewed Original ResearchConceptsPersistent nonunionLong bone nonunionOpen surgical interventionProspective multicenter studySignificant risk factorsAcute fracturesDevastating complicationIntraoperative specimensMulticenter studySurgical interventionFracture nonunionNonunion diagnosisRisk factorsNGS detectionNonunionUseful adjunctFracture healingClinical specimensPatientsClinical implicationsLevel IIMore casesNGS diagnosticsControl casesBacterial profiles
2020
Single-Incision 4-Compartment Fasciotomy of the Lower Leg: Safe, Effective, and Advantageous.
Chang G, Fram B, Krieg JC. Single-Incision 4-Compartment Fasciotomy of the Lower Leg: Safe, Effective, and Advantageous. Orthopedics 2020, 43: e225-e230. PMID: 32271928, DOI: 10.3928/01477447-20200404-03.Peer-Reviewed Original ResearchConceptsAcute compartment syndromeSingle-incision techniqueSkin closureInstances of malunionIntraoperative neurovascular injuryTibial fracture nonunionSingle-incision approachOptimal surgical approachMajority of surgeonsCompartment syndromeComplication rateWound breakdownSingle surgeonNeurovascular injuryRetrospective studySuperficial infectionSurgical approachFracture nonunionPrimary closureSecondary intentionSingle incisionVertical mattress suturesLower LegPatientsFasciotomy
2019
Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report
Fram BR, Strony J, Jagannathan G, Brown SA. Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report. Case Reports In Orthopedics 2019, 2019: 1628980. PMID: 31341689, PMCID: PMC6612392, DOI: 10.1155/2019/1628980.Peer-Reviewed Original ResearchBasal cell carcinomaMetastatic BCCCell carcinomaHistory of BCCMetastatic basal cell carcinomaCutaneous basal cell carcinomaRate of metastasisCommon skin cancerBone metastasesOsseous metastasesCase reportOrthopedic oncologistAppropriate treatmentCorrect diagnosisAge 50Orthopaedic literatureSkin cancerUnknown originCarcinomaMetastasisPatientsSkin pigmentationLight skin pigmentationFirst reportReport
2018
Surgical transposition for chronic instability of the extensor carpi ulnaris tendon
Fram B, Wall LB, Gelberman RH, Goldfarb CA. Surgical transposition for chronic instability of the extensor carpi ulnaris tendon. Journal Of Hand Surgery (European Volume) 2018, 43: 925-930. PMID: 29742949, DOI: 10.1177/1753193418773036.Peer-Reviewed Original ResearchConceptsExtensor carpi ulnaris tendonCarpi ulnaris tendonDorsal transpositionTendon instabilityPROMIS Pain Interference scoresPain interference scoresEffective surgical optionPre-injury levelUpper extremity scorePost-surgical patientsPatients' overall satisfactionAvailable outcome dataHigh-level athletesSurgical transpositionSymptom resolutionSurgical treatmentSurgical optionsExtremity scoreOutcome dataChronic instabilityInterference scoresPatientsLevel athletesTendonSurgery
2014
Outcomes After Involved-field Radiation Therapy (IFRT) With or Without Rituximab in Patients With Early-stage Low-grade Non-Hodgkin Lymphoma (NHL) Staged With CT and PET
Lukens JN, Nasta SD, Fram B, Glatstein E, Plastaras JP. Outcomes After Involved-field Radiation Therapy (IFRT) With or Without Rituximab in Patients With Early-stage Low-grade Non-Hodgkin Lymphoma (NHL) Staged With CT and PET. American Journal Of Clinical Oncology 2014, 37: 35-40. PMID: 22992623, DOI: 10.1097/coc.0b013e31826106c9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntibodies, Monoclonal, Murine-DerivedAntineoplastic AgentsConfounding Factors, EpidemiologicDisease-Free SurvivalFemaleFollow-Up StudiesHumansLymphoma, Non-HodgkinMaleMiddle AgedNeoplasm GradingNeoplasm StagingPositron-Emission TomographyRadiotherapy, Computer-AssistedRetrospective StudiesRituximabTomography, X-Ray ComputedTreatment OutcomeConceptsInvolved field radiation therapyProgression-free survivalNon-Hodgkin lymphomaLow-grade non-Hodgkin lymphomaPositron emission tomographyIndolent non-Hodgkin lymphomaComputed tomographyWeekly dosesRadiation therapyFavorable progression-free survivalImproved progression-free survivalOverall progression-free survivalReceipt of rituximabRituximab-treated patientsUse of rituximabPFS ratesMore patientsProspective studyHistorical controlsRetrospective analysisRituximabPatientsStage IIEmission tomographySignificant differences