2017
0720 ASSOCIATION OF INDIVIDUAL PERIODIC LIMB MOVEMENTS AND NON-SUSTAINED TACHYCARDIA DURING SLEEP: A CASE-CROSSOVER ANALYSIS
May A, May R, Bena J, Wang L, Monahan K, Stone K, Cawthon P, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0720 ASSOCIATION OF INDIVIDUAL PERIODIC LIMB MOVEMENTS AND NON-SUSTAINED TACHYCARDIA DURING SLEEP: A CASE-CROSSOVER ANALYSIS. Sleep 2017, 40: a266-a267. DOI: 10.1093/sleepj/zsx050.719.Peer-Reviewed Original ResearchPeriodic limb movementsRespiratory eventsOsteoporotic fracturesUnadjusted analysesNational InstituteSympathetic nervous system activationBidirectional case-crossover designLimb movementsControl periodNon-sustained tachycardiaApnea-hypopnea indexNervous system activationConditional logistic regressionVentricular tachycardia eventsCase-crossover analysisCase-crossover designAdvancing Translational SciencesPLMS indexBlood InstituteNational HeartTachycardia eventsVentricular arrhythmogenesisOdds ratioAncillary studiesNSVT
2016
Restless Legs Syndrome and Depression: Effect Mediation by Disturbed Sleep and Periodic Limb Movements
Koo BB, Blackwell T, Lee HB, Stone KL, Louis ED, Redline S, Group O. Restless Legs Syndrome and Depression: Effect Mediation by Disturbed Sleep and Periodic Limb Movements. American Journal Of Geriatric Psychiatry 2016, 24: 1105-1116. PMID: 27526989, PMCID: PMC5241001, DOI: 10.1016/j.jagp.2016.04.003.Peer-Reviewed Original ResearchConceptsSevere restless legs syndromeRestless legs syndromePeriodic limb movementsDepressive symptomsLegs syndromeSleep disturbancesMild restless legs syndromeFurther adjustmentAssociation of RLSLimb movementsCardiovascular risk factorsApnea-hypopnea indexBody mass indexPotential mediatorsCross-sectional analysisEffect sizeDopaminergic medicationMass indexOsteoporotic fracturesPLMS indexDisturbed sleepRisk factorsGDS scoresPhysical activitySleep efficiency
2014
Periodic Limb Movements During Sleep and Prevalent Hypertension in the Multi-Ethnic Study of Atherosclerosis
Koo BB, Sillau S, Dean DA, Lutsey PL, Redline S. Periodic Limb Movements During Sleep and Prevalent Hypertension in the Multi-Ethnic Study of Atherosclerosis. Hypertension 2014, 65: 70-77. PMID: 25287399, PMCID: PMC4268086, DOI: 10.1161/hypertensionaha.114.04193.Peer-Reviewed Original ResearchConceptsSystolic blood pressurePLMS-arousal indexPeriodic limb movementsPrevalent hypertensionBlood pressureOverall cohortPLMS indexArousal indexObserved systolic blood pressureLimb movementsCardiovascular risk factorsBlood pressure outcomesApnea-hypopnea indexCommunity-dwelling menBody mass indexType/doseMulti-Ethnic StudyRace/ethnicityAntihypertensive medicationsPLMS frequencyDiastolic BPMass indexPressure outcomesRisk factorsSBP values