2024
Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?
Huelsboemer L, Knoedler L, Kochen A, Yu C, Hosseini H, Hollmann K, Choi A, Stögner V, Knoedler S, Hsia H, Pomahac B, Kauke-Navarro M. Cellular therapeutics and immunotherapies in wound healing – on the pulse of time? Military Medical Research 2024, 11: 23. PMID: 38637905, PMCID: PMC11025282, DOI: 10.1186/s40779-024-00528-5.Peer-Reviewed Original ResearchConceptsStandard of careChronic wound healing disordersLocal wound irrigationWound healingChronic inflammatory microenvironmentFree flap techniqueWound healing disordersChronic woundsGenetic risk profilesPhysiological wound healingAdequate blood supplySurgical debridementFlap techniqueCellular therapyCurrent therapiesHealing disordersInflammatory microenvironmentWound irrigationNon-healing woundsCellular therapeuticsGeneral anesthesiaFormation of biofilmsWound debridementSkin graftsImmunotherapy
2014
Wound healing in acutely injured fascia
Lau F, Pomahac B. Wound healing in acutely injured fascia. Wound Repair And Regeneration 2014, 22: 14-17. PMID: 24813359, DOI: 10.1111/wrr.12165.Peer-Reviewed Original ResearchConceptsFascial healingIncisional herniaApparent functional deficitsSpecific surgical methodsFascial wound healingPaucity of dataHealing failureAcute injuryFunctional deficitsSurgical methodsSurgical proceduresSuch herniasMedical costsClinical settingHerniaClinical methodsFasciaWound healingHealingUnexpected findingRecent studiesSuch healingFailureCeliotomyPatients
2013
Rehabilitation Following Hand Transplantation
Bueno E, Benjamin M, Sisk G, Sampson C, Carty M, Pribaz J, Pomahac B, Talbot S. Rehabilitation Following Hand Transplantation. Hand 2013, 9: 9-15. PMID: 24570631, PMCID: PMC3928383, DOI: 10.1007/s11552-013-9568-8.Peer-Reviewed Original ResearchRehabilitation protocolHand transplantationRehabilitation therapyDaily living trainingUpper extremity amputeesMaximization of functionUnique needsUtility of interventionsHand allotransplantationMotion exercisesJoint contracturesTransplant operationScar adhesionFunctional assessmentNerve regenerationElectrical stimulationExtremity amputeesScar managementTherapy protocolsTransplantationTherapyHand protectionWound healingHand rehabilitationProgressive increase
2010
Meshed Skin Grafts Placed Upside Down Can Take If Desiccation Is Prevented
Zuhaili B, Aflaki P, Koyama T, Fossum M, Reish R, Schmidt B, Pomahac B, Eriksson E. Meshed Skin Grafts Placed Upside Down Can Take If Desiccation Is Prevented. Plastic & Reconstructive Surgery 2010, 125: 855-865. PMID: 20195112, PMCID: PMC2848958, DOI: 10.1097/prs.0b013e3181ccdc42.Peer-Reviewed Original ResearchConceptsSkin graftsMeshed graftReepithelialization rateSplit-thickness skin graftMeshed skin graftAutologous split-thickness skin graftWound environmentFull-thickness woundsHistologic specimensAccelerated reepithelializationDay 4GraftHigh contraction rateWound contractionSheet graftsWound healingWoundsYorkshire pigsSignificant differencesSurvivalHealingRegular graftsReepithelializationContraction rateCurrent study
1998
Dermatan Sulfate Released after Injury Is a Potent Promoter of Fibroblast Growth Factor-2 Function*
Penc S, Pomahac B, Winkler T, Dorschner R, Eriksson E, Herndon M, Gallo R. Dermatan Sulfate Released after Injury Is a Potent Promoter of Fibroblast Growth Factor-2 Function*. Journal Of Biological Chemistry 1998, 273: 28116-28121. PMID: 9774430, DOI: 10.1074/jbc.273.43.28116.Peer-Reviewed Original ResearchConceptsWound fluidDermatan sulfateFactor 2 activityFibroblast growth factor-2Growth factor 2Factor 2 functionHuman wound fluidPotent mediatorSulfated glycosaminoglycan concentrationsSyndecan-1Fibroblast growth factor‐2 activityWound repairWound healingCell proliferationFGF-2Glycosaminoglycan concentrationSoluble proteoglycanFactor 2Immunoblot analysisVivo sourceHeparan sulfatePotent promoterFirst evidenceSyndecan-4Proteoglycans