2022
Maternal blood metal concentrations are associated with C-reactive protein and cell adhesion molecules among pregnant women in Puerto Rico
Kim C, Cathey A, Watkins D, Mukherjee B, Rosario-Pabón Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Maternal blood metal concentrations are associated with C-reactive protein and cell adhesion molecules among pregnant women in Puerto Rico. Environmental Epidemiology 2022, 6: e214. PMID: 35975168, PMCID: PMC9374188, DOI: 10.1097/ee9.0000000000000214.Peer-Reviewed Original ResearchVascular cell adhesion moleculeC-reactive proteinLevels of C-reactive proteinAssociated with C-reactive proteinCell adhesion moleculesAdverse birth outcomesIntercellular adhesion moleculeFetal sexAdhesion moleculesBirth outcomesPregnant womenLinear mixed effects modelsVisit 3Visit 1Maternal C-reactive proteinCustomized Luminex assaySignificant associationBlood samplesPositive associationPrenatal metal exposureWeeks gestationLuminex assayMale fetusesBirth cohortAssessed associations
2021
Gestational Hormone Concentrations Are Associated With Timing of Delivery in a Fetal Sex-Dependent Manner
Cathey A, Watkins D, Rosario Z, Vega C, Mukherjee B, O’Neill M, Loch-Caruso R, Alshawabkeh A, Cordero J, Meeker J. Gestational Hormone Concentrations Are Associated With Timing of Delivery in a Fetal Sex-Dependent Manner. Frontiers In Endocrinology 2021, 12: 742145. PMID: 34603214, PMCID: PMC8479114, DOI: 10.3389/fendo.2021.742145.Peer-Reviewed Original ResearchConceptsTime of deliveryFetal sexBody mass indexGestational ageMaternal agePreterm premature rupture of membranesPre-pregnancy body mass indexHormone concentrationsFetal sex-specific effectsPremature rupture of membranesOverall preterm birthPreterm premature ruptureSpontaneous preterm laborRupture of membranesReduced gestational ageOdds of PTBTime of laborSignificant public health problemTobacco smoke exposureGestational hormonesSpontaneous PTBPreterm laborWeeks gestationPreterm birthLongitudinal birth cohortMaternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates
Aung M, Ashrap P, Watkins D, Mukherjee B, Rosario Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates. Scientific Reports 2021, 11: 8115. PMID: 33854141, PMCID: PMC8046995, DOI: 10.1038/s41598-021-87472-9.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthBiomarkers of pregnancy outcomesGestational age neonatesPreterm birthAge neonatesPregnancy outcomesDegree of hydrocarbon chain saturationIncreased riskNeonatal anthropometric parametersAssociated with increased riskPlasmenyl phosphatidylethanolamineMaternal lipidomeWeeks gestationGestational ageLipidomic signatureAnthropometric parametersLiquid chromatography tandem mass spectrometryLipidomic profilesLipid metabolitesHydrocarbon chain saturationPlasma samplesBirthLogistic regressionHigh-performance liquid chromatography tandem mass spectrometryNeonates
2016
Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia
Cantonwine D, Meeker J, Ferguson K, Mukherjee B, Hauser R, McElrath T. Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia. Environmental Health Perspectives 2016, 124: 1651-1655. PMID: 27177253, PMCID: PMC5047771, DOI: 10.1289/ehp188.Peer-Reviewed Original ResearchRisk of preeclampsiaUrinary concentrations of BPAUrinary concentrations of bisphenol APhthalate metabolitesUrinary concentrationsAssociated with increased risk of preeclampsiaHazard ratioCases of preeclampsiaNested case-control studyDevelopment of preeclampsiaProspective birth cohort studyAssociated with increased riskPhthalate metabolite concentrationsCox proportional hazards modelsAdjusted Cox proportional hazards modelsCase-control studyAdjusted hazard ratiosCalculate hazard ratiosProportional hazards modelBirth cohort studyWeeks gestationPreterm birthAssociated with onsetPreeclampsiaUrinary BPA