Featured Publications
To weight or not to weight? The effect of selection bias in 3 large electronic health record-linked biobanks and recommendations for practice
Salvatore M, Kundu R, Shi X, Friese C, Lee S, Fritsche L, Mondul A, Hanauer D, Pearce C, Mukherjee B. To weight or not to weight? The effect of selection bias in 3 large electronic health record-linked biobanks and recommendations for practice. Journal Of The American Medical Informatics Association 2024, 31: 1479-1492. PMID: 38742457, PMCID: PMC11187425, DOI: 10.1093/jamia/ocae098.Peer-Reviewed Original ResearchEHR-linked biobanksNational Health Interview Survey dataHealth Interview Survey dataPhenome-wide association studyMichigan Genomics InitiativeElectronic health record-linked biobankTarget populationInterview Survey dataColorectal cancerUS adult populationSelection biasUK BiobankAssociation estimatesBiobank dataRecruitment strategiesEffect of selection biasICD codesLog odds ratioUKBSelection weightsEffect sizeAssociation studiesAdult populationBiobankImpact prevalence
2024
Associations of maternal blood metal concentrations with plasma eicosanoids among pregnant women in Puerto Rico
Kim C, Cathey A, Park S, Watkins D, Mukherjee B, Rosario-Pabón Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Associations of maternal blood metal concentrations with plasma eicosanoids among pregnant women in Puerto Rico. The Science Of The Total Environment 2024, 928: 172295. PMID: 38588744, DOI: 10.1016/j.scitotenv.2024.172295.Peer-Reviewed Original ResearchConceptsAdverse birth outcomesSex-specific associationsBirth outcomesBlood metal concentrationsMetal concentrationsPregnant womenInfant sexEicosanoid profileMetal exposurePlasma eicosanoidsWeeks of pregnancyDecreased concentrations of CdConcentrations of CdConcentrations of CuEffect modificationRegulating inflammatory responsesBirth cohortAssessed associationsAssociated with increased concentrationsPregnancy outcomesFemale fetusesEffect sizeInflammatory activitySignificant associationInflammatory response