Decoding the molecular script of 2′-O-ribomethylation: Implications across CNS disorders
Verma A, Roy B, Dwivedi Y. Decoding the molecular script of 2′-O-ribomethylation: Implications across CNS disorders. Heliyon 2024, 10: e39036. PMID: 39524798, PMCID: PMC11550049, DOI: 10.1016/j.heliyon.2024.e39036.Peer-Reviewed Original ResearchRibosomal RNARibosome functionRibosomal RNA structuresPeptidyl transferase centerPost-transcriptional modificationsDefective ribosome biogenesisRibosome biogenesisRibosome integrityRNA modificationsRegulatory networksTranslational efficiencyDecoding siteImpaired mRNA translationMRNA translationBase modificationsPathophysiology of CNS disordersCNS disordersRNA integrityProtein synthesisRibosomal dysfunctionRNANeurodegenerative diseasesDisease pathologySpectrum of CNS disordersPrecision medicine