1999
Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells
Matovcik L, Rhee S, Schaefer J, da Cruz e Silva E, Kinder B. Inhibition of protein phosphatase 1 decreases PTH secretion from isolated dispersed parathyroid cells. Molecular And Cellular Endocrinology 1999, 154: 171-177. PMID: 10509811, DOI: 10.1016/s0303-7207(98)00224-x.Peer-Reviewed Original ResearchConceptsParathyroid hormone secretionOkadaic acidPP-1PP-1 activityPTH secretionPlasma membrane markerHormone secretionParathyroid cellsProtein phosphataseBasal PTH secretionTarget of inhibitionSubcellular fractionationPermeabilized cellsBovine cellsMembrane markersSecretory granulesIntact bovineIntact humanSecretionSelective inhibitorCellsPhosphataseOkadaicInhibitionMarkers
1995
DARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid
Matovcik L, Hemmings H, Kinder B. DARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M r 32,000) is a membrane protein in the bovine parathyroid. FEBS Letters 1995, 364: 67-74. PMID: 7750546, DOI: 10.1016/0014-5793(95)00359-h.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain ChemistryCattleDopamine and cAMP-Regulated Phosphoprotein 32Fluorescent Antibody TechniqueIsoenzymesMembrane ProteinsMembranesMicroscopy, ImmunoelectronNerve Tissue ProteinsParathyroid GlandsPhosphoprotein PhosphatasesPhosphoproteinsProtein Phosphatase 1Protein PrenylationSubcellular FractionsTissue DistributionConceptsProtein phosphatase 1 gammaDARPP-32Protein phosphatase-1 inhibitorPhosphatase-1 inhibitorImmunocytochemical localization studiesMembrane proteinsIntracellular membranesPlasma membraneMetabolic labelingProtein presentLocalization studiesBovine parathyroidImmunoblot analysisSoluble formParticulate fractionDistinct formsMembraneCentral nervous systemCellsM NaClNervous systemParathyroid cellsCytoplasmProteinVesicles