Poorly differentiated ("insular") carcinoma of the thyroid gland: an aggressive subset of differentiated thyroid neoplasms.
Flynn S, Forman B, Stewart A, Kinder B. Poorly differentiated ("insular") carcinoma of the thyroid gland: an aggressive subset of differentiated thyroid neoplasms. Surgery 1988, 104: 963-70. PMID: 3194848.Peer-Reviewed Original ResearchConceptsTotal thyroidectomyInsular carcinomaDisease 1 yearMajority of patientsAggressive clinical courseExternal beam irradiationDifferentiated thyroid neoplasmsEntire neoplasmFocal recurrenceNode dissectionAggressive treatmentClinical courseFatal courseLocal recurrenceDistant metastasisInitial diagnosisDifferentiated carcinomaAggressive subsetTumor necrosisPapillary carcinomaSuch aggressive behaviorThyroid carcinomaInsular componentPatientsCarcinoma