2018
Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study. Toxins 2018, 10: 401. PMID: 30274305, PMCID: PMC6215171, DOI: 10.3390/toxins10100401.Peer-Reviewed Original ResearchConceptsRestless legs syndromePain scoresCrossover studyLegs syndromePlacebo-controlled crossover studyDouble-blind placeboPatient Global ImpressionVisual analog scalePrevious smaller studiesCommon movement disorderQuality of lifeIncobotulinumtoxin APlacebo groupRLS symptomsAnalog scaleGlobal ImpressionOnabotulinumtoxin ALife QuestionnaireTibialis anteriorBotulinum toxinNormal salineMovement disordersRLS scoresSmall studyFemoris muscle
2016
Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain
Machado D, Kumar A, Jabbari B. Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain. Toxins 2016, 8: 374. PMID: 27983689, PMCID: PMC5198568, DOI: 10.3390/toxins8120374.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painVisual analog scaleOswestry Low Back Pain Disability QuestionnaireAbobotulinum toxin ABack painQuality of lifeToxin APain Disability QuestionnairePatient Global ImpressionLevel of painPrimary outcome measureProportion of respondersStrong analgesic effectAbobotulinum toxinOswestry scorePlacebo groupAnalgesic effectDisability QuestionnaireMore patientsStudy cohortAnalog scaleGlobal ImpressionMultifactorial pathophysiologyPatients' perceptions
2009
Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study
Miller D, Richardson D, Eisa M, Bajwa RJ, Jabbari B. Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study. Pain Medicine 2009, 10: 1012-1017. PMID: 19594841, DOI: 10.1111/j.1526-4637.2009.00658.x.Peer-Reviewed Original ResearchConceptsVisual analog scaleRefractory neck painNeck painExcellent respondersPrimary outcomeMean visual analog scaleAdministration of BoNTEfficacy of BoNTUnits of BoNTChronic neck painPlacebo-controlled studyDouble-blind studyImprovement of ADLBotulinum neurotoxinPlacebo groupAnalgesic effectBotox groupFrequency questionnaireSecondary outcomesPain intensityPain localizationPain QuestionnaireAnalog scaleBlinded studyAnimal studies