Brain metastasis in breast cancer: a comprehensive literature review
Rostami R, Mittal S, Rostami P, Tavassoli F, Jabbari B. Brain metastasis in breast cancer: a comprehensive literature review. Journal Of Neuro-Oncology 2016, 127: 407-414. PMID: 26909695, DOI: 10.1007/s11060-016-2075-3.Peer-Reviewed Original ResearchConceptsHuman epithelial growth factor receptor 2Brain metastasesBreast cancerEstrogen receptorMultiple metastasesPositive tumorsProgesterone receptorLonger survivalNovel therapiesWhole-brain radiation therapyBrain metastasis diagnosisAxillary node metastasesBrain radiation therapyGrowth factor receptor 2Primary breast cancerPR-positive tumorsExtra-cranial metastasesMedian time intervalHER2-positive tumorsBlood-brain barrierFuture therapeutic targetsFactor receptor 2Hormonal therapyMost patientsSurgical resection