Multilayer network analysis reveals instability of brain dynamics in untreated first-episode schizophrenia
Gao Z, Xiao Y, Zhu F, Tao B, Zhao Q, Yu W, Sweeney J, Gong Q, Lui S. Multilayer network analysis reveals instability of brain dynamics in untreated first-episode schizophrenia. Cerebral Cortex 2024, 34: bhae402. PMID: 39375878, DOI: 10.1093/cercor/bhae402.Peer-Reviewed Original ResearchConceptsDorsal attention networkFirst-episode schizophreniaNetwork switching rateAntipsychotic treatmentSchizophrenia patientsReduction of negative symptomsResting-state functional magnetic resonance imaging dataUntreated first-episode schizophreniaDrug-naive schizophrenia patientsHealthy controlsFunctional magnetic resonance imaging dataEarly-stage schizophreniaFirst-episode drug-naive schizophrenia patientsInferior parietal lobuleFunctional network activityBrain network activityMagnetic resonance imaging dataNetwork activityAntipsychotic medicationNegative symptomsParietal lobuleAcute psychosisParietal regionsSchizophreniaMultilayer network analysisApplications of MRI in Schizophrenia: Current Progress in Establishing Clinical Utility
Sun H, Liu N, Qiu C, Tao B, Yang C, Tang B, Li H, Zhan K, Cai C, Zhang W, Lui S. Applications of MRI in Schizophrenia: Current Progress in Establishing Clinical Utility. Journal Of Magnetic Resonance Imaging 2024 PMID: 38946400, DOI: 10.1002/jmri.29470.Peer-Reviewed Original ResearchMagnetic resonance imagingTreatment outcome of schizophreniaOutcome of schizophreniaSevere mental illnessSchizophrenia patientsSchizophreniaIllness onsetPredicting symptomsBrain abnormalitiesClinical utilityMental illnessTreatment outcomesDecades of researchFindings of magnetic resonance imagingScreening high-risk individualsLife of affected individualsHigh-risk individualsPromote clinical translationResonance imagingIncreased mortality rateResponse processApplication of magnetic resonance imagingSymptomsPrognostic toolResearch findings