2018
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning
Allsop S, Wichmann R, Mills F, Burgos-Robles A, Chang C, Felix-Ortiz A, Vienne A, Beyeler A, Izadmehr E, Glober G, Cum M, Stergiadou J, Anandalingam K, Farris K, Namburi P, Leppla C, Weddington J, Nieh E, Smith A, Ba D, Brown E, Tye K. Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. Cell 2018, 173: 1329-1342.e18. PMID: 29731170, PMCID: PMC6345560, DOI: 10.1016/j.cell.2018.04.004.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexObservational fear conditioningFear conditioningBasolateral amygdalaThreat-predictive stimuliAssociative fear conditioningImpaired acquisitionAversive cuesCingulate cortexPredictive cuesDemonstrator mouseCue informationAversive valueObservational learningCuesElectrophysiological recordingsRouting of informationAmygdalaCortexMiceStimuliPunishmentSurvival toolInhibition
2015
Decoding Neural Circuits that Control Compulsive Sucrose Seeking
Nieh E, Matthews G, Allsop S, Presbrey K, Leppla C, Wichmann R, Neve R, Wildes C, Tye K. Decoding Neural Circuits that Control Compulsive Sucrose Seeking. Cell 2015, 160: 528-541. PMID: 25635460, PMCID: PMC4312417, DOI: 10.1016/j.cell.2015.01.003.Peer-Reviewed Original ResearchConceptsVentral tegmental areaVentral tegmental area dopamineNeural circuitsReward-predictive cuesFeeding-related behaviorsSucrose seekingReward omissionReward processingReward availabilityTegmental areaHungry miceGABA neuronsLH neuronsGABAergic projectionsDopamineRewardLearning actionsInhibitory inputsNeuronsTherapeutic interventionsSeekingCuesDisordersGABAFood consumption