2013
Novel PI3Kγ Mutation in a 44-Year-Old Man with Chronic Infections and Chronic Pelvic Pain
Bojarski E, Strauss A, Fagin A, Plantinga T, Hoischen A, Veltman J, Allsop S, Granadillo V, William A, Netea M, Dimitrakoff J. Novel PI3Kγ Mutation in a 44-Year-Old Man with Chronic Infections and Chronic Pelvic Pain. PLOS ONE 2013, 8: e68118. PMID: 23861857, PMCID: PMC3704649, DOI: 10.1371/journal.pone.0068118.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmphotericin BAntifungal AgentsBase SequenceChronic DiseaseClass Ib Phosphatidylinositol 3-KinaseDNA Mutational AnalysisExomeFlow CytometryGranulocyte-Macrophage Colony-Stimulating FactorHumansImmunoglobulins, IntravenousLeukocyte CountMaleMolecular Sequence DataMutationPelvic PainReproducibility of ResultsConceptsChronic pelvic painPelvic painChronic infectionChronic purulent sinusitisLong-term treatment regimensCellular immune responsesAntifungal therapyPurulent sinusitisCandida speciesTreatment regimensProstatic fluidWork-upImmune responseSymptom improvementMissense mutationsLeukocyte functionRas-binding domainPainDebilitating symptomsInfectionMutationsSymptomsSignaling elementsRegimensRash
2011
The Role of Phenotyping in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Mahal BA, Cohen JM, Allsop SA, Moore JB, Bhai SF, Inverso G, Dimitrakoff JD. The Role of Phenotyping in Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Current Urology Reports 2011, 12: 297-303. PMID: 21533747, DOI: 10.1007/s11934-011-0196-y.Peer-Reviewed Original ResearchConceptsChronic prostatitis/chronic pelvic pain syndromeChronic pelvic pain syndromeCP/CPPSPelvic pain syndromePain syndromeChronic pain syndromeCurrent symptom-based diagnosesSymptom-based diagnosisUnderlying biological mechanismsTreatment approachesClinical approachCurrent diagnosisSyndromeSuccessful managementDiagnosisTreatmentBiological mechanismsCPPSPainPathogenesisSymptomsMonths