2018
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning
Allsop S, Wichmann R, Mills F, Burgos-Robles A, Chang C, Felix-Ortiz A, Vienne A, Beyeler A, Izadmehr E, Glober G, Cum M, Stergiadou J, Anandalingam K, Farris K, Namburi P, Leppla C, Weddington J, Nieh E, Smith A, Ba D, Brown E, Tye K. Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. Cell 2018, 173: 1329-1342.e18. PMID: 29731170, PMCID: PMC6345560, DOI: 10.1016/j.cell.2018.04.004.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexObservational fear conditioningFear conditioningBasolateral amygdalaThreat-predictive stimuliAssociative fear conditioningImpaired acquisitionAversive cuesCingulate cortexPredictive cuesDemonstrator mouseCue informationAversive valueObservational learningCuesElectrophysiological recordingsRouting of informationAmygdalaCortexMiceStimuliPunishmentSurvival toolInhibition
2014
Optogenetic insights on the relationship between anxiety-related behaviors and social deficits
Allsop S, Vander Weele C, Wichmann R, Tye K. Optogenetic insights on the relationship between anxiety-related behaviors and social deficits. Frontiers In Behavioral Neuroscience 2014, 8: 241. PMID: 25076878, PMCID: PMC4099964, DOI: 10.3389/fnbeh.2014.00241.Peer-Reviewed Original ResearchAnxiety-related behaviorAutism spectrum disorderAnxiety disordersSocial deficitsSocial behaviorBasolateral amygdalaVentral hippocampusSpectrum disorderPathogenesis of social anxiety disorderModulating anxiety-related behaviorsRates of co-morbiditySocial anxiety disorderModulate social behaviorPsychiatric disease statesNeural circuit mechanismsComplex emotional statesPsychiatric illnessPsychiatric diseasesInvestigation of neural circuitsCircuit mechanismsAnxietyNeural circuitsEmotional statesSocial domainsDeficits