2023
Shared Lifestyle‐Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention
Masoudkabir F, Mohammadifard N, Mani A, Ignaszewski A, Davis M, Vaseghi G, Mansourian M, Franco C, Gotay C, Sarrafzadegan N. Shared Lifestyle‐Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention. The Scientific World JOURNAL 2023, 2023: 2404806. PMID: 37520844, PMCID: PMC10386903, DOI: 10.1155/2023/2404806.Peer-Reviewed Original Research
2022
Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer?
Masoudkabir F, Malekzadeh R, Yavari N, Zendehdel K, Mani A, Vasheghani-Farahani A, Ignaszewski A, Toma M, Roayaei P, Turk-Adawi K, Sarrafzadegan N. Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer? Archives Of Iranian Medicine 2022, 25: 50-63. PMID: 35128912, DOI: 10.34172/aim.2022.08.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseRisk factorsOpium consumptionOpium abuseCardiovascular diseaseRisk of ASCVDLifestyle-related risk factorsASCVD risk factorsInadequate physical activityExcessive alcohol consumptionTypes of cancerKinds of cancersPotential carcinogenic effectsDiabetes mellitusPathophysiologic mechanismsOpium abusersUnhealthy dietPhysical activityCurrent evidenceAlcohol consumptionHeart attackCancerCarcinogenic effectsPoor controlDisease
2021
How Are Epigenetic Modifications Related to Cardiovascular Disease in Older Adults?
Gharipour M, Mani A, Baghbahadorani M, de Souza Cardoso CK, Jahanfar S, Sarrafzadegan N, de Oliveira C, Silveira EA. How Are Epigenetic Modifications Related to Cardiovascular Disease in Older Adults? International Journal Of Molecular Sciences 2021, 22: 9949. PMID: 34576113, PMCID: PMC8470616, DOI: 10.3390/ijms22189949.Peer-Reviewed Original ResearchAgedCardiovascular DiseasesDNA MethylationEnvironmentEpigenesis, GeneticHumansInflammationLife Style
2017
Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in Adults
Seidelmann SB, Smith E, Subrahmanyan L, Dykas D, Abou Ziki MD, Azari B, Hannah-Shmouni F, Jiang Y, Akar JG, Marieb M, Jacoby D, Bale AE, Lifton RP, Mani A. Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in Adults. Circulation Genomic And Precision Medicine 2017, 10: e001573. PMID: 28087566, PMCID: PMC5245580, DOI: 10.1161/circgenetics.116.001573.Peer-Reviewed Original ResearchConceptsWhole-exome sequencingSudden cardiac deathCardiovascular diseaseClinical diagnosisExome sequencingCardiac deathInherited cardiovascular diseaseCentre of careNovel candidate genesValuable screening toolAdult patientsRisk stratificationPrimary insultCardiac functionGenetic testingScreening toolDiagnosisCVD genesGenetic causeCardiovascular geneticsGenetic panelSuccess rateExome databasesPotential disease associationsPatients
2015
New targets to treat obesity and the metabolic syndrome
Martin KA, Mani MV, Mani A. New targets to treat obesity and the metabolic syndrome. European Journal Of Pharmacology 2015, 763: 64-74. PMID: 26001373, PMCID: PMC4573317, DOI: 10.1016/j.ejphar.2015.03.093.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiovascular DiseasesHumansMetabolic SyndromeMolecular Targeted TherapyObesityRisk FactorsConceptsMetabolic syndromeCardiovascular diseaseGlucagon-like peptide-1 receptor agonistsPancreatic lipase inhibitor orlistatSingle CVD risk factorPeptide-1 receptor agonistsCVD risk factorsEpidemic of obesityLong-term treatmentType 2 diabetesLipase inhibitor orlistatDipeptidyl peptidase IV inhibitorsAnti-diabetic drugsFuture drug developmentTruncal obesitySerotonergic drugsReceptor agonistRisk factorsMelanocortin systemObesityMetabolic traitsSyndromeMetabolic profileIV inhibitorsNew targets